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After struggling out of the gate this season, the Dallas Cowboys will try to get well at the expense of the New York Giants when they meet in an NFC East matchup on Thursday Night Football. Dallas has dominated the series with New York, winning 13 of the past 14 games against the Giants, including six straight. The Cowboys (1-2), who won the division a year ago, are coming off a 28-25 home loss to the Baltimore Ravens. The Giants (1-2), who are 0-2 in the conference and 0-1 in the division, defeated the Cleveland Browns, 21-15, in Week 3.

Kickoff from MetLife Stadium in East Rutherford, N.J., is set for 8:15 p.m. ET. The Cowboys are 5.5-point favorites in the latest Giants vs. Cowboys odds, while the over/under for total points scored is 45.5. Before making any Cowboys vs. Giants picks, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 4 of the 2024 NFL season on an incredible 188-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 42-22 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.    

Now, the model has set its sights on Cowboys vs. Giants and just locked in its picks and NFL predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and NFL betting lines for the spreadmoney line and over/under for Giants vs. Cowboys: 

  • Giants vs. Cowboys spread: Dallas -5.5
  • Giants vs. Cowboys over/under: 45.5 points
  • Giants vs. Cowboys money line: Dallas -241, New York Giants +198
  • DAL: Cowboys are 5-5 on the road since the start of 2023
  • NYG: Giants are 4-5 at MetLife Stadium since the beginning of last season
  • Giants vs. Cowboys picks: See picks at SportsLine

Why you should back the Cowboys

Dallas is led by a solid receiving corps, which has two players with 10 or more receptions through the first three games. Leading the way is fifth-year veteran wide receiver DeeDee Lamb. He has 13 receptions for 218 yards (16.8 average) and one touchdown. He also has three explosive plays, including a 65-yarder, and has converted eight first downs.

Third-year receiver Jalen Tolbert is off to the best start of his career. He has 10 receptions for 136 yards and one touchdown. He has one explosive play of 39 yards and has converted seven first downs. Although he played all 17 games a year ago, he finished with 22 receptions for 268 yards (12.2 average) and two touchdowns. For his career, he has played in 28 games and has made 34 receptions for 416 yards (12.2 average) and three touchdowns with 20 first-down conversions. See which team to pick here.

Why you should back the Giants

Running back Devin Singletary is off to a solid start to the season as he takes over for Saquon Barkley, who is now with the rival Philadelphia Eagles. In three games, Singletary has rushed 42 times for 197 yards (4.7 average) and two touchdowns. He has two explosive plays of 20 or more yards, including a long of 43, and has converted nine first downs. In the passing game, he has nine receptions for 58 yards (6.4 average).

First-round draft pick Malik Nabers has been impressive through three games. The sixth overall pick of the 2024 NFL Draft, he has 23 receptions for 271 yards (11.8 average) and three touchdowns. He has six explosive plays of 20 or more yards, including a long of 28 yards. In a 21-18 loss at Washington in Week 2, he caught 10 passes for 127 yards and one touchdown, converting seven first downs. See which team to pick here.

How to make Cowboys vs. Giants picks

SportsLine's model is leaning Under the total, projecting 44 points. It has also generated an against-the-spread pick that hits in well over 50% of simulations. You can only get the NFL model's picks at SportsLine.

So who wins Cowboys vs. Giants on Thursday Night Football, and which side of the spread cashes in well over 50% of simulations? Visit SportsLine now to see which side of the Cowboys vs. Giants spread to jump on, all from the advanced model that is up well over $7,000 on its NFL picks, and find out.