Jaguars vs. 49ers Live updates Score, results, highlights, for Sunday's NFL game

The San Francisco 49ers have enjoyed the comforts of home their last two games, but now they must head out on the road. They will take on the Jacksonville Jaguars at 1 p.m. ET on Sunday at TIAA Bank Field. The 49ers should still be riding high after a big victory, while Jacksonville will be looking to regain their footing.

San Francisco took their contest against the Los Angeles Rams this past Monday by a conclusive 31-10 score. San Francisco's WR Deebo Samuel did his thing and punched in one rushing touchdown in addition to catching five passes for one TD and 97 yards.

Meanwhile, Jacksonville was within a late touchdown of stealing the win, but they took the "L" against the Indianapolis Colts 23-17. WR Jamal Agnew put forth a good effort for the losing side as he punched in one rushing touchdown. That touchdown -- a 66-yard rush in the first quarter -- was one of the highlights of the game.

San Francisco is the favorite in this one, with an expected 6.5-point margin of victory. Those who got lucky with them against the spread this past Monday might want to hold off on placing bets this time since the squad has yet to string together back-to-back wins against the spread.

The 49ers' victory brought them up to 4-5 while the Jaguars' loss pulled them down to 2-7. San Francisco is 1-2 after wins this year, and Jacksonville is 2-4 after losses.