Week 1 of the 2024 NFL regular season wraps up on Monday Night Football between the New York Jets and San Francisco 49ers. Both teams have aspirations of being Super Bowl contenders and have played each other 14 times in history, with the 49ers leading the all-time series 11-3, including a 4-2 record at home. In 2020, the Jets were defeated by San Francisco, 31-13, at MetLife Stadium in their last meeting. 49ers running back Christian McCaffrey is inactive with a calf injury.
Kickoff from Levi's Stadium in Santa Clara, Calif, is set for 8:15 p.m. ET. San Francisco is a 3.5-point favorite in the latest Jets vs. 49ers odds via SportsLine consensus, while the over/under for total points scored is 43. Before locking in any 49ers vs. Jets picks, make sure to check out the NFL predictions and betting advice from the SportsLine Projection Model.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 1 of the 2024 NFL season on an incredible 181-129 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 35-21 roll on top-rated NFL picks since Week 7 of 2022.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, the model has simulated Jets vs. 49ers 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and NFL betting lines on the spread, money line and over/under for 49ers vs. Jets betting:
- Jets vs. 49ers spread: San Francisco -3.5
- Jets vs. 49ers over/under: 43 points
- Jets vs. 49ers money line: 49ers -204, Jets +169
- SF: 49ers have hit the 1H money line in 16 of their last 22 games
- NYJ: Jets have hit the 4Q game total Under in 11 of their last 17 games
- Jets vs. 49ers picks: See picks at SportsLine
Why the 49ers can cover
The 49ers trot out a disruptive defense again in 2024. They have high IQ and relentless players on all three levels. Last season, San Francisco was eighth in the NFL in total defense (303.9), third in rushing defense (89.7), and tied for seventh in total sacks (48). Linebacker Fred Warner is one of the best at his position. He has a nose for the ball to pile up stops.
Last season, he recorded 132 total tackles, six TFLs, 11 pass breakups, and four interceptions. Defensive end Nick Bosa gives the 49ers a dynamic enforcer off the edge. Bosa has an array of moves to generate pressure in the backfield. In his career, the Ohio State product has compiled 209 total tackles, 53.5 sacks, and 10 forced fumbles. He has three seasons with 10-plus sacks as well. See who to back at SportsLine.
Why the Jets can cover
The New York Jets added Tyron Smith, Morgan Moses, and John Simpson to the offensive line this offseason to help protect quarterback Aaron Rodgers and running back Breece Hall. The Iowa State product is an explosive playmaker with the ball in his hands. He can easily accelerate away from defenders, but owns reliable hands as a pass-catcher. In 2023, Hall finished with 994 rushing yards, 591 receiving yards, and nine total touchdowns.
Tight end Tyler Conklin is an additional difference-maker on the offensive end. Conklin does a strong job attacking the seams and will be a security blanket for Rodgers. The Central Michigan product put up 61 catches with a career-high 621 receiving yards and 10.2 yards per reception last year. He finished with 50-plus yards in six outings last season. See who to back at SportsLine.
How to make Jets vs. 49ers picks
SportsLine's model is leaning Under the total, projecting the teams to combine for 43 points. The model also says one side of the spread cashes in over 60% of simulations. Head to SportsLine to see its NFL picks.
So who wins 49ers vs. Jets on Monday Night Football, and which side of the spread cashes over 60% of the time? Visit SportsLine now to see which side of the 49ers vs. Jets spread to back, all from the model that has returned well over $7,000 on top-rated NFL picks, and find out.
