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The 2026 NFL playoffs continue on Saturday with a two-game divisional-round slate. The Buffalo Bills travel to take on the Denver Broncos at 4:30 p.m. ET, followed by San Francisco 49ers at Seattle Seahawks at 8 p.m. ET. Despite it being only a two-game slate, the NFL DFS player pool is still stacked with names like Josh Allen, Jaxon Smith-Njigba and Christian McCaffrey.

Who are the best NFL DFS picks for Saturday, and which sleepers can differentiate your NFL DFS lineups on sites like DraftKings and FanDuel? Before making any NFL daily Fantasy picks for the divisional round on Saturday, be sure to check out the NFL DFS advice, strategy and stacks from SportsLine daily Fantasy expert Mike McClure.

You can also bet props like Smith-Njigba as an anytime TD scorer (-110) using the latest DraftKings promo code, which offers $300 in bonus bets if your bet wins:

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including. In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him could be way up.

Now, McClure has turned his attention to the NFL divisional round Saturday DFS slate and just locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine. 

Top NFL DFS picks for the divisional round on Saturday

One of McClure's top NFL DFS picks for Saturday is McCaffrey. Arguably the most valuable all-around player in daily Fantasy football, McCaffrey, when healthy, has been a dominant force because of his ability to pile up stats as a runner and receiver. That continued on Wild Card Weekend when he piled up 114 yards from scrimmage and two touchdowns against the Eagles. The Seahawks are stingy against opposing running backs, and they did a good job limiting McCaffrey in Week 18. He had 142 scrimmage yards against them in their first matchup, however, so there's plenty of evidence that he'll still be able to return value on the playoff slate. See who else to roster at SportsLine, and bet McCaffrey to go Over 50.5 receiving yards at DraftKings:

McClure is also building around Bills quarterback Josh Allen. His passing stats have been down a bit this year largely due to struggles at wide receiver. He took matters into his own hands in the wild-card round, however, rushing 11 times, which tied his season high. He scored twice on the ground to add to his 273 yards and a score through the air. The Bills get a tough matchup against the Broncos, so you can expect Allen to use his feet again to move the ball. See more NFL DFS picks at SportsLine, and bet Allen to go Over 37.5 rushing yards at DraftKings:

How to set divisional round Saturday NFL DFS lineups

McClure is targeting an undervalued player who could explode for huge numbers on Saturday. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of McClure's NFL DFS picks, at SportsLine.

So who is Mike McClure including in his optimal NFL DFS lineups for Saturday, and which under-the-radar player offers huge value? Visit SportsLine now to see optimal NFL DFS picks, NFL DFS rankings, NFL DFS advice and NFL DFS stacks, all from a daily Fantasy expert with more than $2 million in winnings, and find out.