NFL DFS, Buccaneers vs. Texans, Raiders vs. Chargers: Daily Fantasy football picks for Monday Night Football

The Week 2 NFL schedule concludes with a doubleheader on 'Monday Night Football' as the Houston Texans host the Tampa Bay Buccaneers at p.m. ET, and the Las Vegas Raiders host the Los Angeles Chargers at 10 p.. ET. Texans vs. Buccaneers has an over/under of 42.5, while Chargers vs. Raiders has an over/under of 46.5, suggesting both games will be relatively low-scoring affairs. Raiders tight end Brock Bowers (knee) is officially listed as questionable, but coach Pete Carroll told reporters that he expects him to play. 

All eyes will be on the quarterbacks as Justin Herbert, Gene Smith, Baker Mayfield and C.J. Stroud headline the NFL DFS player pool. How should they play into your NFL DFS strategy for MNFs, and which other daily Fantasy picks should be in your NFL DFS lineups? Before locking in any NFL DFS picks on sites like DraftKings and FanDuel, be sure to check out the NFL DFS advice, strategy, and stacks from SportsLine daily Fantasy expert Mike McClure. 

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including. In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him is way up.

Now, McClure has turned his attention to the Monday Night Football doubleheader and just locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine. 

New players can get $50 in Pick6 credits at DraftKings when they play $5: 

Top NFL DFS picks for Bucs-Texans, Chargers-Raiders

One of McClure's top NFL DFS picks for Monday night is Texans wide receiver Nico Collins. The former Michigan standout brings a prototypical WR1 frame at 6-4, 222 lbs, with the length and catch radius to win contested balls downfield. In 2024, he produced 68 catches for 1,006 yards and seven touchdowns in just 12 games, averaging nearly 15 yards per reception and earning his first Pro Bowl nod despite missing time with a hamstring injury.

Across his career since 2021, Collins has tallied 221 receptions for 3,255 yards and 18 scores, consistently flashing big-play ability on the perimeter. His strengths lie in his physicality, vertical separation, and ability to finish in traffic, making him a tough cover for smaller corners. Durability and week-to-week consistency remain the main questions, but when healthy, he profiles as a legitimate WR1 with game-breaking upside. See who else to roster here.

Part of McClure's NFL DFS strategy also includes rostering Chargers wide receiver Ladd McConkey. The former Georgia standout impressed as a rookie in 2024, showcasing polished route-running, quickness, and the ability to create separation at all three levels. At 6-0 and 185 pounds, he lacks elite size but compensates with agility, precise footwork and strong football IQ, making him the top target in the Chargers' passing attack.

McConkey hauled in 82 receptions for 1,149 yards and seven touchdowns across 16 games, averaging 14.0 yards per catch and quickly earning a significant role in the offense. His strengths lie in his suddenness out of breaks, versatility as both a slot and perimeter option, and ability to produce after the catch. See who else to roster here.

New users can see the latest FanDuel promo code to get $300 in bonus bets at FanDuel if your $5 bet wins:

How to set NFL DFS lineups for Monday Night Football

McClure is targeting another undervalued player who could explode for huge numbers on Monday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of McClure's NFL DFS picks, at SportsLine.

So who is Mike McClure including in his optimal NFL DFS lineups for Monday Night Football, and which under-the-radar player offers huge value? Visit SportsLine now to see optimal NFL DFS picks, NFL DFS rankings, NFL DFS advice and NFL DFS stacks, all from a daily Fantasy expert with more than $2 million in winnings, and find out.