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An 11-game Sunday NFL DFS 'main slate' schedule brings a loaded NFL DFS player pool in Week 14. Josh Allen, Lamar Jackson, Ja'Marr Chase, Puka Nacua, Jonathan Taylor and Bijan Robinson are just some of the stars to use in NFL DFS lineups. The game with the highest total is Cardinals vs. Rams (48.5), while Titans vs. Browns (33.5) has one of the lower totals of the season, so knowing the matchups and the projected offensive output will go a long way in help you can in on NFL DFS picks this week. 

How should all that factor into your NFL DFS picks this week, and who are the sleepers in the NFL DFS player pool that can help differentiate your lineups? Before making any NFL DFS picks for Sunday or locking in NFL DFS lineups on sites like DraftKings and FanDuel, be sure to check out SportsLine's advanced NFL DFS lineup optimizer.

New users can also target the latest Underdog promo code, where they can pick at Underdog and get $100 in site credits after making a $5 wager:

The DFS Optimizer uses info from the SportsLine Advanced-Data Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on betting apps like DraftKings and FanDuel. It simulates every game 10,000 times to help DFS players optimize and build winning DraftKings and FanDuel lineups. Optimize, export, and enter lineups confidently with injury updates, floor and ceiling player projections, and Vegas lines and picks all with one winning tool.

Now, SportsLine's NFL DFS Optimizer has turned its attention to Sunday's 2025 NFL Week 14 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine.

New users can get $50 in Pick6 credits at DraftKings when they play $5.

Top NFL Week 14 DFS picks for Sunday

One of the optimizer's top DFS value picks for Sunday is Dolphins running back De'Von Achane at $8,800 on DraftKings and $9,200 on FanDuel. Achane continued his recent heater last week, surpassing 100 yards for the third straight game. He also had a rushing touchdown, his third in the past three weeks. He gets another favorable matchup in Week 14 against the Jets, who have given up the 29th most Fantasy points to opposing running backs. See who else to pick here.

The optimizer's NFL DFS strategy also includes building around Colts tight end Tyler Warren at $6,300 on FanDuel and $5,000 on DraftKings. Warren is the sixth-most targeted tight end in the league, and after failing to score in the first four weeks of the season, he's now recorded four touchdowns over the course of the past eight weeks. The Jaguars have really struggled covering tight ends this year, giving up the 26th most Fantasy points. Brocks Bowers had a massive 12-127-3 line against them last month, so this is  spot where Warren could explode for ig numbers. You can see the rest of the optimizer's NFL DFS picks here.

New users can also check out the latest FanDuel promo code and get $150 in bonus bets at FanDuel if your $5 bet wins

How to build Sunday Week 14 NFL DFS lineups

The NFL DFS Optimizer is also targeting multiple undervalued players who could explode for huge numbers on Sunday. Those players could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who they are, and the rest of the optimizer's NFL DFS picks, at SportsLine

So what is the optimal NFL DFS lineup for Sunday, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice and stacks, all from an NFL DFS optimizer that simulates every game 10,000 times, and find out.