Self-learning AI generates NFL picks, score predictions for every 2026 divisional round matchup
SportsLine AI evaluated the 2026 divisional round NFL odds and revealed its NFL score predictions and best NFL picks
The 2026 NFL divisional round schedule features two games on Saturday, and two on Sunday. Saturday's intriguing matchup will pit NFC West rivals when Bock Purdy and the San Francisco 49ers battle Sam Darnold and the Seattle Seahawks. The Seahawks are favored by 7.5 points at DraftKings Sportsbook in what's the largest divisional round NFL lines. The teams have split two previous playoff meetings.
Other divisional round NFL spreads include Texans vs. Patriots (-2.5) and Rams (-3.5) vs. Bears, both on Sunday. The smallest spread in the divisional round is Bills (-1.5) vs. Broncos. Before making any 2026 NFL divisional round picks or NFL score predictions, you need to see the NFL against the spread, over/under and money line predictions powered by the self-learning SportsLine AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI PickBot has hit more than 2,000 4.5- and 5-star prop picks since the start of the 2023 season.
For 2026 NFL divisional round NFL betting, SportsLine AI has evaluated the NFL odds and provided NFL betting picks for all four games. You can only see the AI predictions for the 2026 NFL divisional round schedule here.
Top 2026 NFL divisional round AI picks
After analyzing every game in the divisional round, the AI says the Broncos (+1.5, 46.5), who were the top seed in the AFC, cover in a tight win.
The Bills have gone under in two of their last three games, while the under has hit in each of the last two Broncos games. Buffalo has won six of the last eight meetings with Denver, including a 31-7 win in an NFC Wild Card matchup last year in Buffalo. The Broncos are looking to win their first postseason game since winning the Super Bowl in 2015.
Buffalo has won two of the last three meetings against the Broncos played in Denver. SportsLine AI rates the Broncos as a B money line pick and also predicts a 24-23 Broncos win on average. See its other 2026 NFL divisional round football predictions and football picks at SportsLine, and bet the Broncos at DraftKings here:
How to make 2026 NFL divisional round picks
In addition, the AI PickBot has generated three highly-coveted A picks for the 2026 NFL divisional round. You need to see the AI's NFL picks before making any 2026 Wild Card Weekend NFL bets of your own. You can only see them at SportsLine.
Who wins and covers each 2026 NFL divisional round game, and which A+ picks should you target now? Visit SportsLine now to see the top NFL picks against the spread, over-under and on the money line, all from the SportsLine AI that has nailed more than 2,000 highly-rated picks since the start of the 2023 season.
