Rookie quarterback Michael Penix Jr. will make his first career NFL start when the Atlanta Falcons host the New York Giants on Sunday. Veteran Kirk Cousins was benched after throwing just one touchdown and nine interceptions over his last five games. Penix will face a New York defense that is giving up 200.4 passing yards per game this season, the seventh-fewest in the NFL. According to the latest Week 16 NFL player prop odds, the rookie quarterback's over/under for total passing yards is 220.5 at FanDuel, while counterpart Drew Lock of the Giants is at 198.5. Should Penix be included in your Week 16 NFL prop picks, or should you target another rookie like Jayden Daniels, Caleb Williams or Drake Maye with your Week 16 NFL player props?

There is plenty of value in the numerous Week 16 NFL props available in the latest Week 16 NFL odds. With sites like DraftKings, FanDuel, PrizePicks, Underdog Fantasy, Sleeper Fantasy, and more offering tons of games surrounding Week 16 NFL player props, you'll want to check out the top Week 16 player props and NFL prop predictions from the SportsLine AI PickBot.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each player prop. The AI predictions are determined by statistically learning from each player's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. SportsLine's AI PickBot has nailed 2,131 4.5- and 5-star prop picks since the start of last season. Anyone who has followed it at their favorite sports betting site and betting apps is way up.    

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For NFL Week 16 NFL betting, the AI PickBot has evaluated the NFL player prop odds and provided prop picks for every position and every available prop market sites like PrizePicks, FanDuel and DraftKings. You can only see the AI player prop predictions for NFL Week 16 at SportsLine.

Top Week 16 QB, RB, WR player prop picks

Here's a look at some of the top Week 16 NFL prop picks from SportsLine AI: 

Quarterback: Jalen Hurts, Philadelphia Eagles: 198.5 passing yards 

Hurts quieted his critics in last week's win over the Steelers, throwing for 290 yards and two touchdowns. He threw the ball 32 times last week, and we could see a similar game plan on Sunday when the Eagles play the Commanders. Hurts completed 18 of 28 pass attempts in his first meeting with Washington this season, finishing with 221 passing yards. The AI PickBot is projecting Hurts will finish with 248.1 passing yards on Sunday, rating the Over as a 4.5-star play. The pick: Over 198.5 passing yards. See more NFL picks here

Running back: Bijan Robinson, Atlanta Falcons: 21.5 receiving yards 

Robinson has eclipsed 1,000 rushing yards in a season for the first time in his career, but he's also been a weapon as a pass catcher. He's hauled in 54 receptions for 411 yards this season, averaging 7.6 yards per catch. He's eclipsed this number in six of his last eight games and he'll be a consistent check-down option for rookie Michael Penix Jr., who's making his first career start in the NFL. The AI PickBot is projecting Robinson will finish with 31.1 receiving yards, rating the Over as a 4.5-star play. The pick: Over 21.5 receiving yards. See more NFL picks here

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Wide receiver: Adam Thielen, Carolina Panthers: 51.5 receiving yards 

Thielen has been effective in recent weeks, recording 22 catches for 252 yards and a touchdown over his last three games. He's coming off his worst performance during that three-game stretch, securing five catches for 51 yards. He's finished with 50 or more receiving yards in each of his last four outings and will take on the Dallas Cowboys on Sunday, a defense that is giving up 217.0 passing yards per game this season. The AI PickBot is projecting Thielen will finish with 66.9 receiving yards, rating the Over as a 5-star play. The pick: Over 51.5 receiving yards. See more NFL picks here

How to make Week 16 NFL prop bets

In addition, the AI PickBot has also locked in confident Week 16 NFL prop picks involving Josh Allen, Aaron Rodgers, Ja'Marr Chase and Kyle Pitts. It's also identified a star quarterback who sails past his total and has 10 other NFL props rated 4.5 stars or better. You must see the AI PickBot's analysis before making any NFL prop bets.

Which NFL prop bets should you target for Week 16, and which star quarterback sails past his total? Visit SportsLine now to see the top Week 16 NFL props, all from the SportsLine AI PickBot that nailed 2,131 top-rated picks since last season.

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