Bills vs. Ravens could be the first game most neutral football fans say they are looking forward to in the Week 4 NFL schedule. Josh Allen and Lamar Jackson are two of the most exciting quarterbacks who can create points with their arms and legs. Allen is 2-1 against Jackson, including the playoffs, with the Bills winning the last two matchups. The Ravens are 2.5-point favorites in the latest Week 4 NFL odds, so should you include either the Bills or Ravens in your Week 4 NFL picks? Week 4 is the final slate before bye weeks begin, so with a jam-packed schedule, which games should you target for your Week 4 NFL predictions? Before you make any Week 4 NFL picks, you need to see the NFL against the spread, over-under, and money line predictions powered by the self-learning SportsLine AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. Last season, SportsLine's AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. Anyone who has followed it is way up.

For Week 4 NFL betting, the AI PickBot has evaluated the NFL odds and provided NFL betting predictions for all 16 games. You can only see the AI predictions for the Week 4 NFL schedule here.

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Top Week 4 NFL AI picks

After analyzing every game in Week 4, the AI PickBot says the Jaguars cover as 5.5-point road underdogs against the Texans. Houston enters at less than full strength with Tank Dell (chest) and Dameon Pierce (hamstring) out. Joe Mixon (ankle) returned to practice on Friday but he's questionable after missing last week, so the Texans could be without their top two running backs again on Sunday. Last week without Mixon and Pierce, the Texans lost 34-7 to the Vikings while rushing for just 38 yards on 2.7 yards per carry.

It has been a tough start for the Jaguars, who are 0-3, but their first two losses came by fewer than six points. The Jaguars are averaging 13.3 points per game, which is 30th in the NFL, but they have many of the same pieces from last year's offense which averaged 22.2 points per game, which was tied with the Texans for 13th-best. The Jaguars have struggled on third down, converting 21.88% this season, but simulations predict Jacksonville's offense isn't nearly as poor as it has shown this season. SportsLine AI has the Jaguars staying within three points of Houston on Sunday. See its other Week 4 football predictions and football picks at SportsLine.

How to make Week 4 NFL picks

In addition, the AI PickBot has generated 11 other A-rated picks for Week 4. You need to see the AI PickBot's picks before making any Week 4 NFL bets of your own. You can only see them at SportsLine.

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Who wins and covers each Week 4 NFL game, and which A-rated picks should you target?  Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the brand-new SportsLine AI PickBot that nailed 1,674 top-rated picks last season.