Several key Houston defenders are active against the 49ers after being listed as probable. They include defensive end J.J. Watt (groin, nose), safety Ed Reed (hip, abdomen), linebacker Brian Cushing (concussion), cornerback Johnathan Joseph (undisclosed), linebacker Bryan Braman (hamstring, shoulder), cornerback Brice McCain (knee), linebacker Darryl Sharpton (foot, hip) and safety Eddie Pleasant (hamstring).