Monday is the ideal time to utilize the latest DraftKings promo code, which gives new users $200 in bonus bets if your first $5 bet wins. Philip Rivers' return to the NFL at age 44 has become one of the most-discussed sports topics of 2025, and on Monday, he'll take the field in front of a national audience when the Indianapolis Colts host the San Francisco 49ers. SportsLine's advanced computer model is backing Rivers and Colts to keep the game competitive, playing the Colts as 5.5-point underdogs as a part of its Monday NFL best bets at DraftKings Sportsbook.

The model also has one of its Monday best bets coming from NBA action, backing the Oklahoma City Thunder to cover as 15.5-point favorites against the Memphis Grizzlies. One of SportsLine's top experts has a pick for Warriors vs. Magic as welll. Claim the latest DraftKings promo code, where new users get $200 in bonus bets if your first $5 bet wins: 

Check out our DraftKings promo code review for full details.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 on a 52-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Monday best bets at DraftKings Sportsbook

  • Colts (+5.5) vs. 49ers
  • Thunder (-15.5) vs. Grizzlies
  • Magic (+5.5) vs. Warriors

Combining the model's three picks into a Monday parlay at DraftKings would result in a payout of +596 (risk $100 to win $596). Bet it at DraftKings here:

Colts (+5.5) vs. 49ers (-110)

The Colts were 14-point underdogs against the Seahawks last week in Philip Rivers' season debut, yet, Indianapolis easily covered the number and nearly pulled off the upset straight-up in an 18-16 final against the Seahawks. The Colts kept the Seahawks out of the end zone for the entire game, resulting in six Seattle field goals and culminating with Jason Myers needing to convert a 56-yard kick with 18 seconds left for the win. Rivers completed 66.7 percent of his passes (18 of 27) for 120 yards, but commanded the offense enough to have the Colts in the game late. Jonathan Taylor rushed for 87 yards, and the model expects Rivers and the offense to make enough plays to keep this contest close as well. The model projects the Colts to cover in 53% of simulations. Back the Colts at DraftKings Sportsbook, where new users get $200 in bonus bets if your first $5 bet wins:

Thunder (-15.5) vs. Grizzlies (-115)

The Thunder have dropped two of their last three games, but that shouldn't create a cause for concern for Monday or the remainder of the season. Oklahoma City still has a chance at a historic season after winning 24 of its first 25 games and opening the season at 25-3 after winning last year's NBA championship. The Grizzlies are without Ja Morant (ankle), and they are coming off a 130-122 home loss on Saturday to the Wizards, which resulted in just Washington's fifth win of the season. Shai Gilgeous-Alexander is having another MVP-caliber season at 32.5 points per game, which ranks second in the league, for OKC. Back the Thunder at DraftKings Sportsbook, where new users get $200 in bonus bets if your first $5 bet wins:

Magic (+5.5) vs. Warriors (-105)

"Some injuries to note both ways here (Franz Wagner out and Jalen Suggs doubtful for Orlando; Steph Curry out for Golden State), but the Magic won't be lacking for confidence after beating the Warriors with Curry by a 121-113 count on November 18 when Desmond Bane scored 23," legendary SportsLine expert Bruce Marshall said. "Note that Orlando was also minus Paolo Banchero for the first meeting, and he has since returned, after Jamahl Mosley's Magic kept things close vs. the Dubs in both meetings during an injury-filled 2024-25 campaign. Steve Kerr has even admitted frustration lately with his Warriors, who had lost three straight before nipping the Suns by 2 in Phoenix on Saturday after losing three of the previous four at Chase Center. Play Magic." Back the Magic at DraftKings Sportsbook, where new users get $200 in bonus bets if your first $5 bet wins:

Want more Monday Night Football, NBA picks for Monday?

You've seen some of the model's Monday best bets. Now, get against the spread, total and money-line picks for all games, including NFL, NBA, college basketball, college football, NHL, and more, all from the model that's simulated every game 10,000 times.