Brock Purdy and the San Francisco 49ers (1-0) will visit Sam Darnold and the Minnesota Vikings (1-0) on Sunday in an NFL Week 2 NFC clash on CBS and Paramount+. The 49ers were without star running back Christian McCaffrey in Week 1, but that didn't stop them from upending Aaron Rodgers and the New York Jets 32-19. The Vikings are coming off of a big win of their own, steamrolling Daniel Jones and the New York Giants, 28-6. McCaffrey is on IR with calf and Achilles injuries. You may be able to stream Sunday's game live on Paramount+, which you can now try free for the first seven days and get 50% off your first year when you sign up here (expires 9/23/24).

Kickoff from U.S. Bank Stadium in Minneapolis is at 1 p.m. ET. The 49ers are 4.5-point favorites in the latest Vikings vs. 49ers odds via the SportsLine consensus, and the over/under for total points scored is 46.5. Sunday's game will be streamed live on Paramount+ with their must-have Paramount+ with SHOWTIME plan, which you can now get for 50% off your first year plus a 7-day free trial.

Paramount+ is the only place to watch every minute of every NFL on CBS game this season. A subscription also gives you access to other sports content including the UEFA Champions League and Europa League, NWSL, Serie A, and countless movies and shows. You can now get 50% off one year of Paramount+ with SHOWTIME, plus a free 7-day trial. The offer is valid until 9/23/24, so sign up right here

How to watch 49ers vs. Vikings

  • Vikings vs. 49ers date: Sunday, Sept. 15
  • Vikings vs. 49ers time: 1 p.m. ET
  • Vikings vs. 49ers TV channel: CBS 
  • Vikings vs. 49ers streaming: Paramount+ 

Week 2 NFL picks for 49ers vs. Vikings

Before tuning into Sunday's Vikings vs. 49ers game, you need to see the NFL picks from SportsLine's advanced computer model. The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2024 NFL season on an incredible 184-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 38-22 roll on top-rated NFL betting picks since Week 7 of 2022.

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For Vikings vs. 49ers, the model is backing San Francisco to cover the spread. The Vikings had a dominant showing in Week 1 against a subpar Giants team, and they will be tested more heavily in Week 2. Darnold will be down a target if No. 2 receiver Jordan Addison can't play because of an ankle injury. The 49ers pass defense did well against the Jets in Week 1 and will be all over Justin Jefferson on Sunday.

Meanwhile, Purdy has plenty of weapons to choose from even if McCaffrey has to miss a second straight game. Jordan Mason made the most of his opportunities against New York and Deebo Samuel continues to pitch in as a helper for the run game. Even if Jefferson can help keep this game close, it's easy to see why the model is high on the 49ers covering in Week 2. You may be able to stream the game here.

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How to watch, live stream the NFL on CBS

Now that you know what to pick, get ready to watch your live local NFL on CBS games on Paramount+ on any device you want. Don't forget you can now try Paramount+ free for the first week and get half-off your first year.