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The Week 2 NFL schedule features an early season matchup between a pair of reigning NFC division champions when the Detroit Lions host the Tampa Bay Buccaneers on Sunday. The Lions are favored by 7.5 points in the Week 2 NFL odds and the game is one of 14 on the Sunday NFL slate. Tampa Bay quarterback Baker Mayfield threw four touchdown passes in Week 1, and there are several NFL props available for the former No. 1 overall pick on Sunday. The over/under for total passing yards for Mayfield is 252.5 in the latest NFL player props, while his over/under for total completions is 22.5.

Should you target any of these NFL prop bets when building lineups and NFL parlay cards on sites like PrizePicks, Underdog Fantasy, Sleeper Fantasy and DraftKings Pick6? Before making your NFL prop picks and parlay lineups on sites like PrizePicks, Underdog Fantasy, Sleeper, and DraftKings Pick 6, you need to see what SportsLine's proven computer simulation model has to say

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2024 NFL season on an incredible 184-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 38-22 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in on the Week 2 NFL schedule and locked in its top NFL prop picks and predictions on sites like PrizePicks, Sleeper, DraftKings Pick6, and Underdog Fantasy. You can only see them by heading to SportsLine.

Top NFL prop picks for Week 2

For the Sunday NFL slate, one of the model's top prop picks is Ravens quarterback Lamar Jackson going over 218.5 passing yards. Jackson averaged 229.9 passing yards per game during his MVP season in 2023, and he has a pair of elite targets at his disposal in tight end Mark Andrews and wide receiver Zay Flowers. Baltimore also added All-Pro running back Derrick Henry to its offense, and his presence alone should force opponents to keep an extra player in the box to defend the run.

The Ravens host the Las Vegas Raiders in Week 2, and Baltimore is favored by 9.5 points. Not only is the model calling for a Baltimore win, it is also calling for a big day from the two-time MVP. Jackson is projected to throw for 265 yards and two touchdowns on Sunday, easily going over on this Week 2 prop bet. See the model's other Week 2 NFL prop picks right here.

How to make picks on PrizePicks, Underdog Fantasy, Sleeper and DraftKings Pick6

The model has also identified an under-the-radar player who could go off for massive numbers because of a dream matchup. This pick could be the difference between winning your contests or going home with nothing. You can only see who it is, and get the rest of the model's picks, here.

What are the top NFL Week 2 prop picks for PrizePicks, Underdog Fantasy, Sleeper, and DraftKings Pick6? Visit SportsLine now to see the top NFL prop picks and predictions from the SportsLine simulation model that is up well over $7,000 for $100 players on top-rated NFL picks, and find out.