Jones recorded 22 total tackles (11 solo), including 3.0 sacks, two passes defensed, including one interception, and one forced fumble across 12 regular-season games in 2025.
The 34-year-old from Penn State was the Bills' most productive interior pass rusher this season, tallying his highest sack total since his 2017 campaign with the Titans. Additionally, Jones nabbed the first interception of his career in the Week 16 win over the Browns. Set to become an unrestricted free agent this offseason, the veteran will likely find work elsewhere ahead of the 2026 season following the emergence of 2025 fourth-round pick Deone Walker, who operated as the Bills' top interior defensive lineman for most of this season.
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Bills' A.J. Epenesa: Smaller defensive role in 2025
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Epenesa tallied 32 total tackles (17 solo), including 2.5 sacks, and four passes defensed, including two interceptions, over 16 regular-season games in 2025.
The Iowa product saw declines in several statistical categories compared to last season, recording fewer total tackles (39 to 32), sacks (6.0 to 2.5) and forced fumbles (two to zero) while playing significantly less defensive snaps (583 to 434). Despite the reduced workload, he remained an effective rotational edge defender and tied his career high in interceptions. Set to hit unrestricted free agency this offseason, Epenesa will likely explore other opportunities after his role dimished in 2025. He could draw interest from teams in need of a starting-caliber edge rusher ahead of the 2026 season.
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Bills' Deone Walker: Solid rookie campaign in Buffalo
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Walker logged 39 total tackles (17 solo), including 1.0 sacks, and four passes defensed across 17 regular-season games in 2025.
The 2025 fourth-round pick from Kentucky was thrust into action immediately, starting 16 regular-season contests during his rookie campaign. Walker was the Bills' most productive interior defensive lineman, finishing second on the team in tackles for loss (eight) and tying for fourth in passes defensed. The 21-year-old showed up when it mattered most during Buffalo's two playoff games, recording six total tackles and two passes defensed, including an interception of Bo Nix during the divisional-round loss. Walker is expected to remain an integral portion of the Bills' defensive front for years to come.
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Bills' Greg Rousseau: Stays productive in 2025
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Rousseau recorded 46 total tackles (24 solo), including 7.0 sacks, two passes defensed and one forced fumble over 16 regular-season contests in 2025.
The 2021 first-round pick from Miami has emerged as Buffalo's best pass rusher, leading the team in sacks each of the past two seasons. Since entering the league, Rousseau has recorded 7.0-or-more sacks in three of his five campaigns, proving to be one of the league's most consistent pass rushers. Additionally, he wreaked havoc during Buffalo's two playoff games, recording eight total tackles, including 1.0 sacks, and two passes defensed. Under contract through the 2029 season, Rousseau is expected to remain the Bills' top edge rusher in 2026.
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Bills' Dorian Williams: Production dips in 2025
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Williams (neck) recorded 63 total tackles (29 solo) and two passes defensed over 16 regular-season appearances in 2025.
Williams was one of the Bills' best defenders in 2024, recording 117 total tackles across 618 defensive snaps. However, he played a smaller defensive role this season, logging just 63 stops over 431 defensive snaps in the regular season. Despite this, the Tulane product remained a key part of Buffalo's defense, as he tallied the fifth-most stops on the team and was an important special-teams contributor (258 snaps). Still on his rookie contract through the 2026 season, Williams, who left the Bills' divisional-round loss to the Broncos with a neck injury, could compete for a starting inside linebacker position this summer.
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Bills' Terrel Bernard: Output declines in 2025
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Bernard (calf) tallied 65 total tackles (44 solo) and three passes defensed, including one interception, over 12 regular-season contests in 2025.
Bernard has seen vast declines across several statistical categories over the last two seasons, recording fewer total tackles (143 to 65), sacks (6.5 to zero), passes defensed (five to three) and interceptions (three to one) compared to his 2023 campaign. However, his 2025 season was cut short by injuries, as he missed five regular-season contests and both of the Bills' playoff games. Bernard was one of Buffalo's best tacklers when healthy, recording the fourth-most stops on the team. Under contract through 2029, the Baylor product is expected to remain one of the Bills' top inside linebackers in 2026.
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Bills' Matt Milano: Healthier in 2025
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Milano recorded 67 total tackles (36 solo), including 3.5 sacks, and one forced fumble over 12 regular-season appearances in 2025.
Entering the 2025 season, Milano had played just nine regular-season games over the past two years due to a plethora of injuries. His 12 appearances this year marked his highest total since the 2022 campaign. The 31-year-old remained an impactful defender when on the field, ranking third among Buffalo defenders in both total tackles and sacks. Now set to enter unrestricted free agency this offseason, Milano will likely land a short-term deal with a team in need of a starting-caliber inside linebacker ahead of the 2026 season, though he's never played for anybody but the Bills and could be back.
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Bills' Jordan Poyer: Continues to produce in Buffalo
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Poyer (hamstring) logged 70 total tackles (31 solo), including 0.5 sacks, and three passes defensed, including one interception, across 10 regular-season games in 2025.
The 34-year-old safety from Oregon State began the season on Buffalo's practice squad, but a season-ending injury to Taylor Rapp (knee) allowed Poyer to play a larger defensive role. After returning to the starting lineup in the Week 8 matchup against the Panthers, Poyer emerged as one of the Bills' top tacklers, finishing with the second-most stops on the team. Set to become an unrestricted free agent this offseason, he could return to Buffalo as a reliable depth option if injuries impact the secondary again in 2026. Poyer played in the Bills' first playoff game against the Jaguars, but he suffered a hamstring injury in that game and was unable to play in the divisional round.
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Bills' Cam Lewis: Returns vs. Denver
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Lewis (undisclosed has returned to Buffalo's divisional-round matchup versus the Broncos on Saturday, Katherine Fitzgerald of The Buffalo News reports.
Lewis is back in action after briefly exiting the game at the end of the first half due to cramping. Darnell Savage filled in at safety while Lewis was sidelined.
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Bills' Cam Lewis: Questionable to return
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Lewis (cramps) is questionable to return Buffalo's divisional-round matchup versus the Broncos on Saturday.
Lewis is currently dealing with cramping, which caused him to exit the game late in the first half. Darnell Savage will replace Lewis at safety if he ends up being unable to return.
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Bills' Ed Oliver: Good to go Saturday
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Oliver (biceps/knee) is active for Buffalo's divisional-round matchup versus the Broncos on Saturday, Alec White of the team's official site reports.
Oliver is officially set to make his return to the field after having been activated off injured reserve Friday. The 28-year-old has been sidelined since tearing his biceps during the Week 8 win over the Panthers back in October and should resume his role as one of the team's starting defensive tackles against Denver.
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Bills' Terrel Bernard: Ruled out vs. Denver
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Bernard (calf) is inactive for Buffalo's divisional-round matchup versus the Broncos on Saturday, Alec White of the team's official site reports.
Bernard managed to be a limited participant in practice throughout the week but will nonetheless be sidelined for a third consecutive game. In his absence, Dorian Williams and Joe Andreessen could see increased playing time, while Bernard will look to return next week during the AFC Championship Game should the Bills defeat Denver.
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Bills' Damar Hamlin: Remains on IR
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Hamlin (pectoral) wasn't activated from injured reserve Friday, ruling him out for Saturday's divisional-round game against the Broncos.
Hamlin was designated for return from injured reserve nine days ago and logged a trio of full practices this week. However, it wasn't enough for the Bills to activate him ahead of Saturday's playoff contest. With Jordan Poyer (hamstring) ruled out against Denver, the Bills will be down to Cole Bishop, Sam Franklin, Jordan Hancock, Cam Lewis and Darnell Savage as options at safety.
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Bills' Ed Oliver: Activated from injured reserve
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The Bills activated Oliver (biceps/knee) from injured reserve Friday.
Oliver suffered a torn biceps in October and then underwent a cleanup procedure on his knee last month. He's listed as questionable for Saturday's divisional-round tilt with the Broncos. Oliver's return would be a massive boost to a Buffalo defense that has been gashed by opposing running backs seemingly all season.
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Bills' Greg Rousseau: Ready to rock
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Rousseau (back) has no injury designation ahead of Saturday's divisional-round matchup against the Broncos.
The 2021 first-round pick from Miami practiced in a limited capacity throughout the week, but it now appears he's moved past his back injury in time to play in the divisional round. Rosseau is coming off an impressive performance in the Bills' wild-card win over the Jaguars, recording six total tackles, including 1.0 sacks, and one pass defensed over 44 defensive snaps. Now fully healthy, he's expected to start opposite Joey Bosa during Saturday's playoff contest.
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Bills' A.J. Epenesa: Past neck issue
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Epenesa (neck) has no injury designation ahead of Saturday's divisional-round matchup against the Broncos.
The 27-year-old from Iowa practiced in a limited fashion throughout the week, but it now appears he's moved past his neck injury in time to play Saturday. Epenesa operated as one of Buffalo's top defensive ends during the regular season, recording 32 total tackles, including 2.5 sacks, and four passes defensed, with two interceptions, over 16 appearances. Back at full health, he's expected to play behind Joey Bosa and Greg Rousseau during the divisional-matchup in Denver.
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Bills' Shaq Thompson: Ready for Saturday
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Thompson (neck) has no injury designation ahead of Saturday's divisional-round matchup against the Broncos.
Despite practicing in a limited fashion Wednesday and Thursday due to a neck injury, Thompson will suit up for Saturday's playoff contest. The 31-year-old delivered a huge performance in the Bills' wild-card win over the Jaguars, recording eight total tackles and an interception. Now fully healthy, Thompson is expected to remain one of Buffalo's top linebackers during the divisional round.
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Bills' Ed Oliver: Questionable for Saturday
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Oliver (biceps/knee) will practice in a limited fashion Thursday and is listed as questionable for Saturday's divisional-round matchup against the Broncos, Joe Buscaglia of The Athletic reports.
Oliver was designated to return from the injured reserve list Tuesday and has since logged three consecutive limited practices. If the 28-year-old gets added to the Bills' active roster in time to play Saturday, it would be a significant addition to Buffalo's defense, as he's recorded 12 total tackles, including 3.0 sacks, and one forced fumble in just three appearances this season. However, if Oliver cannot return for the divisional round, Deone Walker and DaQuan Jones would likely remain Buffalo's top interior defensive linemen.
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Bills' Matt Milano: Logs limited practice Wednesday
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Milano (ankle) was limited in practice Wednesday.
Milano logged his second straight limited practice after opening the week on the injury report with an ankle injury. The 31-year-old's status for the Bills' AFC divisional round matchup against the Broncos will likely depend on his participation in practice Thursday.
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Bills' Maxwell Hairston: Absent again
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Hairston (ankle) was not on the field during Wednesday's practice, Alaina Getzenberg of ESPN.com reports.
Hairston was unable to participate in the Bills' wild-card victory over the Jaguars last Sunday due to an ankle injury that kept him out of practice during the week. The rookie cornerback has continued the trend of nonparticipation through Week 20, missing consecutive practices to start the week. Unless Hairston can upgrade his participation level in Thursday's session, he will likely miss the Bills' divisional round matchup with the Broncos on Saturday as well.