NFL Sunday has arrived, and the Week 6 NFL odds have seen some noticeable shifts throughout the week. After opening at -1.5, the Eagles are now 3-point underdogs at home against the Panthers after quarterback Jalen Hurts (blood clot) was placed on injured reserve. Panthers vs. Eagles kicks off at 1 p.m. ET. Other notable Week 6 NFL lines include Jets vs. Patriots (-7), Bills vs. Raiders (+5.5), Chargers vs. Chiefs (-7.5) and Cowboys vs. Packers (-1.5). Bet on every Week 6 NFL game with the latest DraftKings promo code, where new users get $200 in bonus bets plus 3 months of NBA League Pass after making a $5 wager: 

Below you'll find the NFL betting odds for every Week 6 matchup. You can find the SportsLine Projection Model's NFL betting advice for Week 6 here. Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get a $55 bonus:

** Odds provided by DraftKings are subject to change **

Sunday, Oct. 18

Jacksonville Jaguars vs. Houston Texans

Spread: Jaguars -2.5
Moneyline: Jaguars (-148), Texans (+124)
Total: 42.5  

Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the bet365 bonus code CBSBET365:

Atlanta Falcons vs. Chicago Bears

Spread: Bears -1.5
Moneyline: Falcons (-102), Bears (-118)
Total: 52.5  

Claim the Caesars Sportsbook promo code CBSSPORTSBR250 here and get your bonuses:

Cleveland Browns vs. Baltimore Ravens

Spread: Ravens -3
Moneyline: Browns (+140), Ravens (-166)
Total: 39.5

Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get a $55 bonus:

Indianapolis Colts vs. Tennessee Titans

Spread: Colts -7
Moneyline: Colts (-340), Titans (+270)
Total: 44.5  

Bet on NFL games with the latest DraftKings promo code and get $200 in bonus bets and 3 months of NBA League Pass after making a $5 wager: 

New England Patriots vs. New York Jets

Spread: Patriots -7.5
Moneyline: Patriots (-340), Jets (+270)
Total: 43.5  

Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:

New York Giants vs. New Orleans Saints

Spread: Saints -1.5
Moneyline: Saints (-110), Giants (-110)
Total: 46.5  

Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:

Philadelphia Eagles vs. Carolina Panthers

Spread: Panthers -3
Moneyline: Panthers (-166), Eagles (+140)
Total: 39.5  

Claim the Caesars Sportsbook promo code CBSSPORTSBR250 here and get your bonuses:

Tampa Bay Buccaneers vs. Pittsburgh Steelers

Spread: Steelers -2.5
Moneyline: Buccaneers (+124), Steelers (-148)
Total: 38.5

Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get a $55 bonus:

Los Angeles Rams vs. Arizona Cardinals

Spread: Rams -12.5
Moneyline: Rams (-750), Cardinals (+525)
Total: 51.5  

Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the bet365 bonus code CBSBET365:

Kansas City Chiefs vs. Los Angeles Chargers

Spread: Chiefs -7.5
Moneyline: Chiefs (-455), Chargers (+350)
Total: 41.5  

Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:

Las Vegas Raiders vs. Buffalo Bills

Spread: Bills -5.5
Moneyline: Raiders (+185), Bills (-225)
Total: 53.5  

Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:

Green Bay Packers vs. Dallas Cowboys

Spread: Packers -1.5
Moneyline: Packers (-118), Cowboys (-102)
Total: 53.5  

Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get a $55 bonus:

Monday, Oct. 19

San Francisco 49ers vs. Washington Commanders

Spread: 49ers -7.5
Moneyline: 49ers (-455), Commanders (+350)
Total: 52.5  

Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:

Add CBS Sports on Google