WORCESTER, Mass. (AP) Grant Breneman threw for two touchdowns and ran in two more Saturday to lead Colgate to a 45-7 win over Holy Cross.

Breneman was 16 of 24 for 222 yards passing, including a 59-yard touchdown throw to Thomas Ives midway through the third quarter to make it 30-7. Ives finished with three receptions for 92 yards, and James Holland had 109 yards with a 1-yard touchdown as Colgate (4-4, 2-1 Patriot League) dominated with 419 total yards of offense while holding Holy Cross to 97 yards rushing and 271 overall.

Also scoring for Colgate was Nick Diaco, who snagged a 12-yard touchdown throw from Breneman for the game's first score, and a 24-yard interception return by Dillon DeIuliis that ended the opening drive of the second half.

Colgate notched its largest-ever margin of victory over Holy Cross (2-6, 1-2) in 80 series meetings.

Peter Pujals connected with Andre Harton in the first quarter on a 7-yard touchdown for Holy Cross that tied the game at 7. Pujals was 13 of 24 for 154 yards passing with three interceptions.

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