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The Shillelagh Trophy is up for grabs for the first time since 2021 when Notre Dame plays Purdue on Saturday during the Week 3 college football schedule. The trophy was first presented in 1957 and from 1946-2014, Notre Dame vs. Purdue was an annual rivalry matchup in college football. After a six-year hiatus, they met in 2021 in South Bend and Purdue will host the 2024 matchup. Notre Dame is 57-26-2 all-time against Purdue and the Boilermakers haven't defeated Notre Dame since 2007.

The contest will kick off from Purdue's Ross-Ade Stadium in Indiana on Saturday at 3:30 p.m. ET. Notre Dame is a 7.5-point favorite in the latest Notre Dame vs. Purdue odds via SportsLine consensus. The over/under for total points scored is 47. Before making any Purdue vs. Notre Dame picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

Saturday's game can be seen live on CBS and streamed live on Paramount+, which you can now get for 50% off your first year plus a 7-day free trial (valid through 9/22/24).

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 4-0 start on over/under picks this season. Anyone who has followed it has seen strong returns.

Now, the model has dialed in on Notre Dame vs. Purdue and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's picks. Here are the college football odds and trends for Purdue vs. Notre Dame:

  • Notre Dame vs. Purdue spread: Fighting Irish -7.5
  • Notre Dame vs. Purdue over/under: 47 points 
  • Notre Dame vs. Purdue money line: Notre Dame -284, Purdue +227
  • Notre Dame vs. Purdue picks: See picks here
  • Notre Dame vs. Purdue streaming: Paramount+ (get 50% off first year of annual plan now through 9/22/24)

Why Notre Dame can cover

Notre Dame went 19-7 over the first two years under head coach Marcus Freeman with a bowl victory in each season. The Fighting Irish have won at least nine games in seven straight seasons, including six seasons with double-digit wins. Last week is going to be a tough loss for Notre Dame to completely forget about, but after defeating No. 20 Texas A&M, 23-13, in College Station in Week 1, this year's Fighting Irish team has the potential to be one of the best teams in the nation.

Notre Dame climbed to No. 5 after starting the season at No. 7 following the Texas A&M victory. The Fighting Irish are down to No. 18 after the home loss to Northern Illinois and a standout defense is a main reason for the top-10 preseason ranking. Cornerback Benjamin Morrison is one of the best defensive backs in the country and leads a Notre Dame pass defense that is holding opposing quarterbacks to a 44% completion percentage, which ranks seventh in college football. See picks at SportsLine

Why Purdue can cover

Purdue enters its second season under head coach Ryan Walters and it took the Boilermakers only one game this season to match their season-high for scoring and record its most-lopsided victory under Walters with a 49-0 win over Indiana State on Aug 31. Although Notre Dame is a significant leap of difficulty from an FCS school, the Fighting Irish did just suffer a massive upset against Northern Illinois, a MAC squad.

There is more familiarity within the Purdue program this fall with Walters having a full season with the program. He also returns starting quarterback Hudson Card and that comfort clearly showed against Indiana State when the fifth-year senior completed 24 of 25 passes for 273 yards and four touchdowns. The Boilermakers also return their leading rusher in Devin Mockobee, who rushed for 89 yards on 8.1 yards per carry in Week 1 after rushing for 807 yards with 180 receiving yards last year. See picks at SportsLine

How to make Notre Dame vs. Purdue picks

SportsLine's model is leaning Over on the total, projecting 51 combined points. It also says one side of the spread hits nearly 60% of the time. You can see the model's pick at SportsLine.

So who wins Purdue vs. Notre Dame, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out, and don't forget to stream on Paramount+.