The No. 5 Indiana Hoosiers can essentially secure their spot in the College Football Playoff with a win over No. 2 Ohio State on Saturday afternoon during the Week 13 college football schedule. Indiana has won its first 10 games of the season, but it has not faced a ranked opponent. The Hoosiers are 13.5-point underdogs in the Week 13 college football odds, as they have not beaten Ohio State since 1988. Should you fade Indiana with your Week 13 college football bets?

There are a pair of other ranked vs. ranked matchups on Saturday, including No. 21 Arizona State (-3) vs. No. 14 BYU and No. 6 Notre Dame (-14.5) vs. No. 19 Army. The Black Knights join Indiana and No. 1 Oregon as the only unbeaten teams remaining in college football. Before making any Week 13 college football picks and college football score predictions, you need to see the college football against the spread, over/under and money-line predictions powered by the self-learning SportsLine AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

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In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI PickBot has hit a whopping 2,029 4.5- and 5-star NFL picks since the start of last season. Anyone who has followed it is way up at their best sports betting app and favorite betting sites

For Week 13 college football betting, the AI PickBot has evaluated the college football odds and provided college football betting picks for every game. You can only see the AI predictions for the Week 13 college football schedule here.

Top Week 13 college football AI picks

After analyzing every game in Week 13, the AI PickBot says the No. 8 Miami (FL) Hurricanes (-25, 64.5) cover comfortably at home against the Wake Forest Demon Deacons in a noon ET kickoff on Saturday. Miami is guaranteed to play in the ACC title game if it wins its final two regular-season games, so focus is not going to be an issue for the Hurricanes. They are led by Heisman Trophy candidate Cam Ward, who leads the nation in passing yards (3,494) and passing touchdowns (32). 

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The Hurricanes lost to Georgia Tech earlier this month, but they had a bye last week to reset and prepare for this contest. They lead the country in points per game (45), and Wake Forest has allowed 30 or more points seven times this season. The AI PickBot has identified value on Miami, projecting the Hurricanes win by an average final score of 48-19 to earn an A+ rating. See its other Week 13 college football predictions and football picks at SportsLine.

How to make Week 13 college football picks

In addition, the AI PickBot has generated 10 more A-rated spread picks for Week 13. You need to see the AI PickBot's college football picks before making any Week 13 college football bets of your own. You can only see them at SportsLine.

Who wins and covers each Week 13 college football game, and which A-rated picks should you target now? Visit SportsLine now to see the top college football picks against the spread, over/under, and on money line, all from the brand-new SportsLine AI PickBot that has nailed 2,029 top-rated NFL picks since the start of last season.

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