Player Bio
| HT/WT: 6-6, 308 lbs |
| Birthplace: Cincinnati, OH |
| Age: 24 |
| School: Illinois |
| Experience: R |
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1:24National Tight Ends Day: Odds to Have Most Rec Yards
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1:17Brock Purdy's Fantasy Value Amid 49ers' Injuries
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12:38Way-Too-Early NFL Season Awards
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0:585 Receivers The Rams Should Target: Vikings WR Jauan Jennings
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1:00Breaking Down NFC North Playoff Chances
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0:59Jamey's Fantasy Start of the Week: Braelon Allen
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1:40Start or Sit: Germie Bernard and Kyle Pitts
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0:45Only 5 NFL Teams Can Win The Super Bowl
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63:03Russell Wilson and Kyle Long react to NFL Week 6: Jalen Hurts news, Caleb Williams' return & more | Set, Hut!
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10:08How the 49ers are undefeated | Set, Hut!
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2:18NFL Week 7 Picks: 49ers at Falcons
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2:00Mike Evans & Terry McLaurin Leave Week 6 With Injuries
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2:40NFL Week 7 Picks: SNF Chiefs at Seahawks
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1:22
49ers WR Mike Evans Leaves Game With Achilles Injury
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0:21Terry McLaurin Carted Off With Knee Injury
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0:54How 49ers Stack Up Against Other Undefeated Teams
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1:19How Potential Mike Evans Loss Impacts 49ers
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1:3849ers' Run Game Perfectly Complements Pass Game
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1:49
Brock Purdy Shines Again, 49ers' Remain Undefeated
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1:51Dan Quinn's Situational Mistakes Costly Again in Commanders Week 6 Loss
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2026 Defensive
| STATS |
CMB
Total Tackles
|
SCK
Sacks
|
FUM
Forced Fumbles
|
INT
Interceptions
|
TD
Interceptions Returned For Touchdown
|
|---|---|---|---|---|---|
| Regular Season | 5 | 0.0 | 0 | 0 | 0 |
Top James Thompson Jr. News
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49ers' James Thompson: Cleared for Week 6
Thompson (ankle) doesn't carry an injury designation into Monday night's game against the Commanders.
Thompson hasn't played since Week 2 against the Dolphins after playing 35 percent of the defensive snaps across the first two weeks of the season. He'll slide back into his depth role along the defensive line before Osa Odighizuwa and Naquan Jones.
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49ers' James Thompson: Approaching return to action
Thompson (ankle) could return to action in Week 6 against Washington, Matt Barrows of The Athletic reports.
Thompson has been sidelined since suffering a high-ankle sprain in Week 2 against Miami, but head coach Kyle Shanahan said Monday that the defensive lineman has "a chance" to play in the team's Week 6 matchup against the Commanders on Monday Night Football. Thompson has registered four total tackles (one solo) over two games this season.
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49ers' James Thompson: Won't play against Seattle
Thompson (ankle) has been ruled out for Sunday's game against the Seahawks.
As expected, Thompson will miss a third consecutive game due to an ankle injury. He didn't practice once during Week 5 prep, so he'll need to return to the field to have a realistic shot of being available for Week 6 against the Commanders on Monday, Oct. 19. Naquan Jones and Sebastian Valdez will both see an uptick in rotational snaps at defensive tackle behind Osa Odighizuwa and Gracen Halton.
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49ers' James Thompson: Expects to be out again at Seattle
Coach Kyle Shanahan said Monday that Thompson (ankle) is not expected back for Week 5, Cam Inman of The San Jose Mercury News reports.
Thompson has already missed the 49ers' last two games with an ankle injury he picked up in Week 2 versus the Dolphins, and it seems like he's trending towards missing another contest come Sunday. In that case, Sebastian Valdez would be a candidate for increased snaps on the defensive line.
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49ers' James Thompson: Won't play Week 4
Thompson (ankle) won't play in San Francisco's Week 4 matchup versus the Broncos, Jennifer Lee Chan of NBC Sports Bay Area reports.
Thompson is in line to miss a second consecutive game due to the high-ankle sprain he suffered during the Week 2 win over the Dolphins. While there's currently no timetable for his return, his next chance to play will be the Week 6 matchup against Seattle.
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49ers' James Thompson: Sidelined versus Arizona
Thompson (ankle) is listed as out for Sunday's game against Arizona.
Thompson suffered a high-ankle sprain in the 35-13 victory over the Dolphins in Week 2. While nothing has been made official, an injury of this nature likely means he will miss more time moving ahead. The rookie appeared in both of the 49ers' games to begin the 2026 campaign, amassing four total tackles (one solo).
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49ers' James Thompson: Likely to miss action moving forward
Thompson suffered a high-ankle sprain during Sunday's 35-13 win over Miami, David Lombardi of SFStandard.com reports.
Thompson sustained the injury in the second half of the victory, and he will now likely be forced to miss some time moving forward. In his absence, the 49ers will have to add another interior defensive lineman to their active roster.
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49ers' James Thompson: Dealing with ankle injury
Thompson (ankle) is questionable to return to Sunday's contest against Miami, Eric Branch of the San Francisco Chronicle reports.
Thompson was slow to get up before ultimately going to the locker room in the second half. His status for the rest of the game is now in the air, but his absence won't have a major impact on the team's defensive approach.
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