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Astros manager Joe Espada said that De Los Santos (knee) is slated to pitch in a game Tuesday, Brian McTaggart of MLB.com reports.

Espada didn't specify whether De Los Santos will be pitching in the Astros' Grapefruit League game against the Pirates that day or in a minor-league game, but either way, it will be the first action of the spring for the 30-year-old righty. De Los Santos has been slowed by a right knee strain suffered at the beginning of camp, but he's since resumed facing hitters and is slated to take part in pitcher's fielding practice Sunday. He shouldn't require much of a ramp-up period and appears on track for Opening Day.

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