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Weiss will start Thursday's game against the Rockies, Brian McTaggart of MLB.com reports.
Weiss has been hit around quite a bit during his last two outings, conceding nine runs (eight earned) on 12 hits and four walks while striking out eight batters over five innings. However, the Astros are running low on options with seven starting pitchers currently on the injured list, so the 29-year-old righty will be called upon to make his first MLB start. He'll at least benefit from a favorable matchup, as the Rockies rank in the bottom third of MLB with a .681 OPS.
Astros' Taylor Trammell: Heading to bench Wednesday
Rotowire
Trammell is out of the lineup for Wednesday's game against the Rockies.
After getting called up from Triple-A Sugar Land on Friday, Trammell has started in three of the Astros' ensuing six games while going a collective 4-for-13 with a double, two walks, three RBI and two runs. He'll likely be part of a timeshare in center field with Joey Loperfido until Jake Meyers (oblique) is ready to return from the injured list.
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Astros' Jose Altuve: Receiving night off
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Altuve is out of the lineup for Wednesday's game against the Rockies.
Per Matt Kawahara of the Houston Chronicle, manager Joe Espada said that Altuve's absence from the lineup is a routine rest day after the 35-year-old infielder started each of Houston's first 18 games. Isaac Paredes will spell Altuve at second base and will bat third.
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Astros' Cody Bolton: Placed on IL with back injury
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The Astros placed Bolton on the 15-day injured list Wednesday with mid-back inflammation, Brian McTaggart of MLB.com reports.
Bolton was lifted from his previous start Sunday against the Mariners with a back issue that had lingered since his previous outing. The injury doesn't seem to be a long-term issue, but the loss of Bolton for any period of time represents yet another blow to the Astros' rotation depth.
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Astros' Spencer Arrighetti: Recalled for season debut
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The Astros recalled Arrighetti from Triple-A Sugar Land on Wednesday, Brian McTaggart of MLB.com reports.
Arrighetti is set to start Wednesday's game at home against the Rockies in what will be his first start with the big club this season. The right-hander had been in a groove with Sugar Land, authoring a 1.26 ERA, 0.77 WHIP and 20:6 K:BB over 14.1 innings in his first three starts. The Houston rotation has been decimated by injuries, providing Arrighetti with an opportunity to stick around indefinitely.
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Astros' Brandon Bielak: Grabs minors deal from Astros
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The Astros signed Bielak to a minor-league contract Wednesday, Tread Athletics reports.
Bielak missed most of the 2025 season following shoulder surgery, but he's healthy now and was sitting in the 90-to-93 mph range recently while pitching for Tecolotes de los Dos Laredos of the Mexican League. Most of the 30-year-old's major-league experience has come with the Astros, though Bielak's last stint in the big leagues came in 2024 with the Athletics. He should be assigned to Triple-A Sugar Land, but it's unclear whether Houston intends to use him as a starter or reliever.
De Los Santos earned the save Tuesday against the Rockies, striking out the only batter he faced.
De Los Santos was called on in the ninth with two outs and runners at the corners after Bryan King allowed back-to-back singles, and he quickly shut the door. The right-hander needed just five pitches to sit down Jordan Beck and secure the win. The save was his first since 2024 and only his fourth in an eight-year career. Since returning from the injured list April 6, De Los Santos has been a reliable bullpen arm, allowing one run while striking out four over 5.2 innings.
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Astros' Colton Gordon: Hit hard in season debut
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Gordon did not factor into the decision Tuesday against the Rockies, allowing four runs on eight hits while striking out five over 3.2 innings.
Making his first start of the season, Gordon was tested early and often. The right-hander gave up a homer to the third batter he faced -- Hunter Goodman -- in the first, then allowed three straight hits in the second inning that led to two more runs. Trouble returned in the fourth when he surrendered another long ball and loaded the bases before being lifted. While the five strikeouts were encouraging, Gordon will need consistently keep traffic off the bases in order to find success in his next scheduled start against St. Louis.
Diaz is out of the lineup for Tuesday's game against the Rockies, Matt Kawahara of the Houston Chronicle reports.
Diaz started the previous three games and will receive a day off after going 2-for-11 with a solo homer and an additional RBI during that stretch. Christian Vazquez will work behind the plate and bat ninth versus Colorado righty Michael Lorenzen.
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Astros' Spencer Arrighetti: Set to start against Colorado
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Arrighetti will be recalled from Triple-A Sugar Land to start against the Rockies on Wednesday or Thursday, Brian McTaggart of MLB.com reports.
Houston's rotation has been hit hard by injuries, losing Cristian Javier (shoulder) and Tatsuya Imai (arm) within the past week alone. Arrighetti will come up to fill one of the vacancies, and his first matchup will come at home against a Rockies offense that's struggled to a .674 OPS through its first 16 games.
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Astros' Tatsuya Imai: Imaging comes back clean
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Imaging on Imai's right arm came back negative, Chandler Rome of The Athletic reports.
Imai landed on the injured list Monday due to right arm fatigue, but he doesn't appear to be dealing with a structural issue. The team now plans to build up the 27-year-old's arm strength before having him begin a throwing progression. It remains unclear how soon he will be able to return to the Astros' rotation.
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Astros' Josh Hader: Throwing live BP
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Hader (biceps) is throwing live batting practice Tuesday, Chandler Rome of The Athletic reports.
The veteran left-hander has been throwing bullpen sessions for a while and has finally been cleared to face live batters after sitting out all of spring training due to biceps inflammation. Making his season debut for the Astros before the end of April still appears to be in play. However, early May seems more realistic for Hader given that he's likely to require a handful of rehab outings in the minors before being fully cleared.
Burrows (1-3) took the loss Monday against the Mariners, allowing six runs on 11 hits and one walk in six innings. He struck out three.
Although Burrows fired 69 of his 98 pitches for strikes and amassed 17 swinging strikes, he was perhaps a bit too haphazard in targeting the zone Monday. The Mariners tagged him for four-extra base hits, with two leaving the yard off the bat of Josh Naylor, and Burrows wound up giving up a career-high 11 hits and matching a career worst in runs allowed. The 26-year-old right-hander is off to a rocky start in his Astros tenure, posting a 6.55 ERA, 1.82 WHIP and 18:7 K:BB over 22 frames, but he'll have an opportunity to turn things around in a favorable home matchup against the Cardinals this weekend.
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Astros' Colton Gordon: Starting Tuesday vs. Colorado
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Gordon will start for the Astros in Tuesday's series opener against the Rockies in Houston, Matt Kawahara of the Houston Chronicle reports.
The Astros recalled Gordon from Triple-A Sugar Land on Monday to give the parent club more depth in the rotation due to Hunter Brown (shoulder), Tatsuya Imai (arm) and Cristian Javier (shoulder) all being placed on the injured list this past week. Gordon appeared in 20 games (14 starts) for the Astros in 2025, posting a 6-4 record with a 5.34 ERA, 1.42 WHIP and 72:19 K:BB across 86 innings. He's been sharp in three starts in Triple-A this season and boasts a 1.76 ERA and 0.98 WHIP over 15.1 frames with Sugar Land.
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