McCullers (elbow) exited Tuesday's game in the fifth inning after experiencing discomfort in his right elbow, Angel Verdejo Jr. of the Houston Chronicle reports.
McCullers will be re-evaluated again Wednesday, and the team will likely give a timetable on his return in the next couple days. He was pitching a solid game at the time of the injury, throwing 48 of his 56 pitches for strikes, although he gave up seven hits and two earned runs.