The Blue Jays recalled De Los Santos from Triple-A Buffalo. He will start at third base and bat eighth Sunday against the Twins.
The 26-year-old received his first taste of the big leagues in late July and early August, though he was sent back to Triple-A after appearing in just three games. De Los Santos has been productive at Triple-A this season with six home runs and a .260/.375/.441 slash line in 43 games.