Toronto designated Ramirez for assignment Sunday.
The 30-year-old righty reliever was bumped off the 40-man roster to make room for another bullpen arm in Ryan Tepera (elbow), who was reinstated from the 60-day injured list. Over 22 appearances between the Indians and Blue Jays this season, Ramirez has posted a 5.40 ERA and 1.64 WHIP across 25 innings.