Perdomo started at designated hitter and went 1-for-4 with an RBI for Triple-A Reno on Thursday.
Perdomo, who played seven innings at shortstop Wednesday, was in the lineup for a second straight day but got replaced by a pinch hitter after eight innings. Perdomo will continue his rehab assignment through the weekend for Reno and could rejoin the Diamondbacks next week. Arizona begins a homestand Tuesday against the Angels.