Guillorme started at second base and went 1-for-5 with a stolen base in Wednesday's 10-8 win over Miami.
Guillorme made his debut for the Diamondbacks, who signed him earlier in the week in the wake of starting second baseman Ketel Marte (ankle) landing on the injured list. He's expected to serve as the backup at the keystone while Marte is sidelined, but the lefty-swinging Guillorme provides a useful complement to primary fill-in Kevin Newman.