The Giants activated Estrada (wrist) from the 10-day injured list Monday, Alex Pavlovic of NBC Sports Bay Area reports.
Estrada missed the last three-plus weeks with a left wrist sprain but is ready to go after a five-game rehab stint which saw him go 9-for-21 with one home run. He's starting at second base and batting eighth Monday versus the White Sox in his return to action. Brett Wisely was sent down to Triple-A Sacramento in a corresponding move.