Flores is out of the lineup for Monday's game against the Cubs.
Flores had started at first base in each of the Giants' last five games, with three starts coming versus lefties and two coming versus right-handers. Though the Giants seem content to deploy Flores as their primary first baseman rather than a platoon bat while LaMonte Wade (hamstring) is on the injured list, Flores will nonetheless give way to rookie Trenton Brooks on Monday.