Rodriguez was pulled from Wednesday's game against Baltimore due to hamstring spasms, Ryan Divish of The Seattle Times reports.
Manager Dan Wilson said that Rodriguez's hamstring began to bother him after he made a leaping grab in center field, so the Mariners took him out of the game as a precaution. The team may err on the side of caution and hold him out of Thursday's series finale as well, though no decision has been made just yet.