Despaigne was optioned to Triple-A New Orleans on Sunday.
Despaigne was knocked around to the tune of eight runs during his Saturday start, but the right-hander isn't completely to blame, as two fielding errors led to five of those runs being unearned. Nonetheless, the Marlins will send him down to the minors in favor of additional bullpen help in the series finale. With a team day off next Thursday, the organization is likely hopeful that either Wei-Yin Chen (arm fatigue) or Edinson Volquez (thumb) will be able to come off the disabled list for what would have been Despaigne's next turn in the rotation Friday.