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The Orioles designated Castillo (undisclosed) for assignment Sunday.

Shortly after the Orioles claimed him off waivers from the Mariners on May 7, Castillo was placed on Triple-A Norfolk's 7-day injured list due to an unspecified injury. He made pair of rehab starts in the rookie-level Florida Complex League earlier this month and was reinstated from Norfolk's IL on Sunday, only to be simultaneously removed from the Orioles' 40-man roster to make room for right-hander Matt Bowman, whose contract was selected from Triple-A.

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