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Santana (back) is starting at first base Friday against the Cardinals, Kevin Gorman of TribLive.com reports.

Santana was forced to miss three games after exiting Sunday's game against Seattle with back tightness, but the 37-year-old first baseman will return to action Friday. Santana has been struggling at the plate as of late, slashing .176/.288/.294 over the past three weeks.

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