Lyles allowed one walk and struck out two over two scoreless innings in Tuesday's 4-1 loss to Arizona.
Lyles, who is the Rangers' No. 5 starter, is not part of the first rotation due to off days during the first weeks of the season. To keep him fresh for an expected starting assignment, manager Chris Woodward was able to afford him multiple innings Tuesday. Lyles is expected to start Saturday on the road against the Giants.