Seigler was removed from Saturday's game after experiencing pain in his right wrist following a swing, MLB.com reports. He hurt the wrist in the fourth inning and was eventually removed in the seventh.
Seigler, who was called up to Boston on Friday as a replacement for Eli White (foot), started at second base before departing. He was replaced by Isiah Kiner-Falefa. Seigler underwent further testing and evaluation following the game.