De Los Santos was optioned to Triple-A Scranton/Wilkes-Barre after Monday's 7-3 loss to the Tigers. He allowed two unearned runs on two hits across two innings of relief.
De Los Santos was brought in with two outs in the top of the second inning Monday and managed to escape a jam, but he gave up two runs in the top of the fourth following a costly error by Cody Bellinger. The Yankees will presumably bring up a fresh bullpen arm ahead of Tuesday's contest after using six relievers Monday.