Trubisky (knee) will be a limited participant during practice Wednesday, Alaina Getzenberg of ESPN.com reports.
Trubisky is still nursing a knee injury suffered in a mid-August preseason tilt with the Steelers. His ability to participate at some level Wednesday should be a step in the right direction, though head coach Sean McDermott is "not sure" if the North Carolina product will be available Week 1, according to Maddy Glab of the Bills' official site. If Trubisky can't play Sunday against the Cardinals, Buffalo will likely promote Mike White to the active roster from the practice squad.