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DiMarco sat out Wednesday's first practice of the week due to an ankle injury, Chris Brown of the Bills' official site reports.
DiMarco hardly ever carries the ball -- he hasn't posted more than two rushes in a season since 2009 and is still looking for his first NFL rushing TD -- but he's the Bills' only true fullback and a strong special teams player, so any potential absence would affect Buffalo's game plan against the Eagles.
