Bryant sustained a high-ankle sprain in Sunday's loss to the Ravens, Jake Trotter of ESPN.com reports.
Coach Kevin Stefanski said Monday that Bryant will be re-evaluated in "a couple weeks" following his diagnosis. The 23-year-old racked up a season-high 50 yards on three receptions against Baltimore. He'll be able to recover during the Browns' Week 13 bye, but it's not yet clear whether he'll be available for the team's Week 14 matchup against the Ravens on Dec. 12.