Smith has been ruled out for Saturday's game against the Eagles due to an ankle injury, Kirk Larrabee of 247sports.com reports.
Smith is one of six Colts cornerbacks who will not be playing on Saturday, leaving the team with just half of their corner's available for the game. The specifics of Smith's injury is unknown beyond being an ankle issue, and it's unclear when he'll be able to return. Look for Christopher Milton and Frankie Williams to see some extra reps with Smith out.