Downs (shoulder) is slated to practice Wednesday, Stephen Holder of ESPN.com reports.
Downs -- who suffered a right shoulder injury in the Colts' Week 12 loss to the Lions -- missed a Week 13 win over the Patriots, but following the team's Week 14 bye, the wideout has progressed to the point that he'll work in some capacity Wednesday. The Colts' first Week 15 injury report will be released later Wednesday and will reveal whether Downs was a limited or full participant to kick off the team's prep for Sunday's game in Denver.