Colts head coach Shane Steichen announced Wednesday that Brents (knee) has been designated for return from injured reserve.
Brents' 21-day practice window will officially open, and he can be added back to the 53-man roster at any point during that timeframe. The 2023 second-round pick is thus eligible to return to action as early as Sunday's game against the Titans, if Indianapolis makes the corresponding transaction. Brents is working his way back from an MCL injury that's kept him sidelined since the Colts' regular-season opener and required surgery.