The Bills cut Murphy on Saturday, Jay Skurski of The Buffalo News reports.
Buffalo's surprising decision to part ways with fellow running back LeSean McCoy wasn't enough to open up a roster berth for Murphy, who likely would have been in line mainly for a special-teams role had he secured a spot. Murphy could still catch on elsewhere as a depth back and return specialist after bringing back a punt 79 yards for a touchdown in Buffalo's preseason finale Thursday.