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The 2025 NFL Wild Card Weekend includes six games spread out over Saturday, Sunday and Monday. While the regular season may be over, playoff Fantasy football will begin this week and you can always use a reliable set of Wild Card Fantasy football rankings and NFL projections to make NFL same-game parlays, enter lineups on NFL DFS sites, and enter NFL props on sites like PrizePicks. Jayden Daniels and the Washington Commanders will visit the Tampa Bay Buccaneers on Sunday and the over-under for total passing yards on Daniels is 233.5.

How will the NFL Offensive Rookie of the Year favorite fare, can you trust him to be among your Wild Card Fantasy football picks, and which NFL prop picks should you target? Before setting your NFL Wild Card Weekend Fantasy football lineups or betting any player props on sites like PrizePicks, be sure to check out the NFL Wild Card Weekend Fantasy football rankings and projections from the proven computer model at SportsLine.

When it comes to ranking players, SportsLine's model beat human experts in Fantasy football for the past several seasons, especially when there were big differences in ranking. Over the course of a season, that could literally be the difference between winning your league or going home empty-handed.

The same model has a proven track record of providing Fantasy football tips, including being ahead of the curve on players like A.J. Brown, Jonathan Taylor, Derrick Henry, Christian McCaffrey, Alvin Kamara, and Jahmyr Gibbs. Anybody who banked on players like those could have made a run at their league title.

Now, SportsLine has simulated the entire Wild Card Weekend NFL schedule 10,000 times and released its latest NFL Wild Card Weekend Fantasy football rankings and projections. Head to SportsLine now to see them.

How to bet on NFL games

Here are several sportsbooks to bet on NFL games this week, along with the various NFL sportsbook promos they currently offer.

SportsbookPromo
Caesars Bet $1, double your winnings on your next 10 bets up to $25 per boost
BetMGMUp to $1,500 in bonus bets if your first bet loses
FanDuelBet $5, get $200 in bonus bets
Bet365Bet $5 and get $150 in bonus bets guaranteed* 
DraftKingsBet $5, get $200 in bonus bets instantly
FanaticsBet up to $100 per day for the first 10 days to get up to $1,000 in no sweat bets

Top NFL Wild Card Weekend Fantasy football QB projections

For NFL Wild Card Weekend 2025, the model projects the top Fantasy football quarterback to be Josh Allen of the Buffalo Bills. Allen is the heavy favorite to win his first NFL MVP after leading the Bills to a 13-4 record and the AFC East championship with a depleted cast. He threw for 3,731 yards and 28 touchdowns and six interceptions while continuing to serve as Buffalo's primary goal-line threat.

Allen rushed for 531 yards and 12 more touchdowns and scored nine rushing touchdowns over the course of his last seven starts. On a weekend where several of the best QBs in the NFL will be in action, the model projects Allen leads all of them in Fantasy scoring with an average of 26.45 points. It predicts that he throws for 222 yards and 1.81 touchdowns on average while also rushing for 34 yards and 0.61 touchdowns. See more top QBs here.

Top NFL Wild Card Weekend Fantasy football RB projections

Another 2025 NFL Wild Card Weekend projection from the model, the top Fantasy football running back is Derrick Henry of the Baltimore Ravens. Despite putting together what may be a Hall of Famer career in Tennessee, Henry was allowed to walk in free agency and joined the Ravens this offseason. At 31, he proceeded to turn in the most productive season of his career on a per-touch basis.

Henry averaged 5.9 yards per carry and finished the year with 1,921 rushing yards and 16 touchdowns. His 18 total touchdowns led the NFL and tied his career-high and the model is predicting that he rushes for 102 yards and 0.94 touchdowns on average against the Steelers on Saturday. It also projects that he outscores superstar running backs like Saquon Barkley, Josh Jacobs and Joe Mixon to be the top-scoring Fantasy football running back. See more top RBs here.

Top NFL Wild Card Weekend Fantasy football WR projections

For NFL Wild Card Weekend 2025, the model also projects the top Fantasy football wide receiver will be Los Angeles Rams superstar Puka Nacua. A fifth-round pick out of BYU last year, Nacua took everybody by surprise by breaking the rookie record for receptions (105) and piling up 1,486 receiving yards and six touchdowns last season. Despite missing six games and playing less than 40% of snaps in two other contests, he was even better on a per-game basis in 2024.

He finished with 79 catches for 990 yards and scored four total touchdowns in 11 games and had five outings where he surpassed 100 receiving yards. That includes a 106-yard outing against the Viking at home on Oct. 24, and the Rams will welcome Minnesota back to SoFi Stadium on Monday. The model predicts that Nacua averages 7.3 catches for 97 yards and 0.40 touchdowns to finish with 20.79 points in PPR leagues on average and lead all wide receivers. See more top WRs here.

Top NFL Wild Card Weekend Fantasy football TE projections

Included in the 2025 NFL Wild Card Weekend projections from the model, the top Fantasy football tight end is predicted to be Mark Andrews of the Baltimore Ravens. Andrews extended his touchdowns streak to six games with four catches for 54 yards and a score against the Browns in Week 18 and led all NFL tight ends with 11 touchdowns on the season.

His eight targets in that outing were also a career-high and he'll be eager to get back onto the field against the Steelers after catching his first career touchdown against Pittsburgh in Week 16. Now the model is projecting that he accounts for a league-high 11.11 Fantasy points on average. It predicts that he catches 3.3 passes for 43 yards and 0.55 touchdowns on average. See more top TEs here.

Top NFL Wild Card Weekend Fantasy football D/ST projections

For NFL Wild Card Weekend 2025, the model projects the top Fantasy football D/ST to be the Los Angeles Rams. They'll host the Minnesota Vikings in the final matchup of NFL Super Wild Card Weekend 2025 on Monday and will try to follow the Detroit Lions' blueprint for disrupting Sam Darnold. After a season that put Darnold into the NFL Comeback Player of the Year race, Darnold went 18-for-41 for 166 yards without a touchdown in a must-win against Detroit last week.

Meanwhile, the Rams defense only allowed 24 points in Weeks 15-17 before choosing to rest starters in Week 18 with the NFC West locked up. The model is projecting that the Rams account for a league-high 10.52 Fantasy points on average. It predicts that they average 3.04 sacks, 1,02 interceptions and 0.69 fumble recovers with 0.17 defensive touchdowns. See more top D/ST here

How to get NFL Wild Card Weekend Fantasy football rankings and projections

Now that you know who the top player at each position is and their projected stats, you'll want to see the full NFL Wild Card Weekend Fantasy football rankings from SportsLine. The model has identified a stunner in the top 10 at wide receiver, and knowing who it is can give you a huge edge in your league. Head to SportsLine now to get NFL Wild Card Weekend Fantasy football rankings and projections.

So who should you target for your playoff Fantasy football leagues, DFS, SGPs and on PrizePicks, and which surprising wide receiver could lead you to a winning week? Visit SportsLine now to get NFL Wild Card Weekend Fantasy Football rankings for every single position, all from the model that has a history of making league-winning calls, and find out.