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Guion (knee) is inactive for Sunday's Week 3 matchup with the Lions, ESPN.com's Rob Demovsky reports.
Guion was listed as doubtful heading into Sunday's game after not practicing all week, so it's unsurprising that he'll sit out after sustaining an MCL sprain in the Week 2 loss to the Vikings. Rookie Kenny Clark will likely see extended snaps with Guion removed from the defensive line rotation.
