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Mixon was a limited participant at practice Wednesday due to ankle injury.

Mixon, who was also deemed limited Tuesday, suffered a minor ankle injury in this past Sunday's win over the Dolphins, but the running back said Wednesday that he anticipates playing Saturday against the Chiefs, according to Aaron Wilson of KPRC 2 Houston. Thursday's injury report will clarify whether or not Mixon heads into the weekend with an injury designation, but at this stage, he looks like he'll be ready to handle his usual role Saturday as Houston's lead back.

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