The Vikings placed McCarthy (knee) on injured reserve Friday.
Minnesota signed quarterback Matt Corral in a corresponding transaction. Head coach Kevin O'Connell had already ruled McCarthy, the No. 10 overall pick in April's draft, out for the season, so his official placement on injured reserve was expected. McCarthy will turn his attention to making a recovery from the surgery he underwent Wednesday to make a full repair of the meniscus in his right knee, while the Vikings turn to Sam Darnold as the Week 1 starter. Corral joins Nick Mullens and second-year quarterback Jaren Hall behind Darnold on the depth chart.