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Qadree Ollison RB | PIT
Falcons' Qadree Ollison: Remains healthy scratch
Ollison (coach's decision) is inactive for Sunday's Week 5 tilt against the Texans.
The rookie will continue to wait on his NFL debut despite the fact fellow running back Kenjon Barner (concussion) is out for a second consecutive week. Brian Hill will continue backing up the top backfield duo of Devonta Freeman and Ito Smith.
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Damien Harris RB | BUF
Patriots' Damien Harris: Inactive Sunday
Harris is inactive for Sunday's game against Washington.
Harris won't suit up Sunday, even with Rex Burkhead (foot) out. In the event that Sony Michel suffers an injury down the road, Harris could factor in on early downs, but in Week 5 the Patriots will roll with a backfield comprised of Michel, James White and Brandon Bolden.
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Devin Singletary RB | NYG
Bills' Devin Singletary: Inactive Sunday
Singletary (hamstring) is inactive for Sunday's game against the Titans.
Following a pregame workout, the Bills elected to play it safe with the rookie running back, especially with a bye coming up in Week 6. As a result, Frank Gore will continue to head the team's ground game Week 5, with T.J. Yeldon on hand to serve as a complementary option.
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Devin Singletary RB | NYG
Bills' Devin Singletary: Status hinges on pregame workout
Singletary (hamstring), who is listed as questionable for Sunday's game against the Titans, will stage a pregame workout before the Bills decide on his status, Ian Rapoport of NFL Network reports.
Fortunately for Singletary's fantasy managers, the Bills and Titans play in the early wave of Sunday's games, so resolution on his status will come when Buffalo releases its inactive list 90 minutes prior to the 1 p.m. EDT kickoff. If Singletary's hamstring issue sidelines him for a third consecutive week, Frank Gore would be in store for another turn as Buffalo's top option on the ground.
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Marlon Mack RB | ARI
Colts' Marlon Mack: Game-time decision
Mack (ankle), who is listed as questionable for Sunday's game against the Chiefs, is considered a game-time call, Ian Rapoport of NFL Network reports.
Mack's ankle injury forced his early removal from the Week 4 loss to the Raiders and prevented him from practicing Wednesday and Thursday. Though Mack was able to put in a full practice Friday, the Colts want to see how he comes out of a pregame warmup before making a call on his status. Nyheim Hines and Jordan Wilkins would benefit from beefier workloads in the event Mack is inactive for the first time this season. An official decision on Mack will come around 6:50 p.m. EDT, when the Colts will unveil their inactive list.
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Aaron Jones RB | MIN
Packers' Aaron Jones: Bell-cow role may await
Jones will likely be in store for an elevated snap count and extra touches with top backfield complement Jamaal Williams (concussion) ruled out for Sunday's game in Dallas, Rob Demovsky of ESPN.com reports. "I definitely think I can go toe-to-toe with him," Jones said earlier this week, when asked how he compares to the Cowboys' three-down back, Ezekiel Elliott. "I feel like that's something I did a couple of years back in Dallas when not a lot of people knew me. That was my first start. I definitely think I can go toe-to-toe."
Jones is specifically referring to the 16-carry, 125-yard performance he turned in as a rookie in 2017, the first time he crossed the 100-yard mark in his career. Aside from a 116-yard outing versus the Vikings in Week 2, Jones has struggled to produce on the ground this season, but the absence of Williams leaves the Packers with few alternatives to turn to in the event the Dallas defense stymies the run game Sunday. Other than Jones, the only remaining backfield options on the 53-man roster are a fullback (Danny Vitale) and a sixth-round rookie who has yet to make his NFL debut (Dexter Williams).
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Melvin Gordon RB | BAL
Chargers' Melvin Gordon: Restricted workload likely on tap
Coach Anthony Lynn suggested Friday that Gordon's workload may be limited in the running back's season debut this weekend against the Broncos, Gilbert Manzano of The Orange County Register reports. "I don't want to put him in there and play him too much, and I really don't have to," Lynn said of Gordon. "I like what Austin Ekeler has been doing."
The Chargers' official site now lists Gordon atop the depth chart at running back, but that doesn't mean he'll immediately take back the nearly 20 touches per game he averaged in 12 regular-season starts in 2018. Since Gordon has only had two weeks of practice time following his 64-day holdout, the Chargers are cognizant of easing him into the mix, with Ekeler's solid performance over the first four games affording the team that luxury. The prospect of a restricted snap/touch count makes Gordon a risky selection in DFS contests, though he might still have a path to enough touches this week to bring value in season-long leagues.
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Austin Ekeler RB | WAS
Chargers' Austin Ekeler: In line to play 'a lot' Week 5
Coach Anthony Lynn said Friday that Ekeler will play "a lot" in Sunday's game against the Broncos, Daniel Popper of The Athletic reports.
Though the team's official site lists Melvin Gordon atop the depth chart at running back, Lynn suggested that the 26-year-old's role will be limited to some extent while he plays in his first game since mid-January. The introduction of Gordon into the game plan hinders Ekeler's fantasy outlook moving forward, but the latter could still offer plenty of value in Week 5 if he ends up taking on the larger share of backfield touches. In the Chargers' first four games sans Gordon, Ekeler has averaged 122.5 total yards and six catches per contest while finding the end zone six times.
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Damien Williams RB | ARI
Chiefs' Damien Williams: Practices fully, listed as questionable
Williams (knee) is listed as questionable for Sunday night's game against the Colts despite practicing fully all week.
That said, Herbie Teope of The Kansas City Star relays that coach Andy said the running back would play this weekend, which makes sense given Williams' participation level at practice throughout the week. Assuming that's the case, Williams figures to join a Week 5 timeshare with LeSean McCoy, while Darrel Williams would be a candidate to work in a complementary/backup role.
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Saquon Barkley RB | PHI
Giants' Saquon Barkley: Out this week, but practices Friday
The Giants listed Barkley (ankle) as a limited participant on their Friday injury report, though he's already been ruled out for Sunday's game against the Vikings.
The limited listing suggests Barkley took a step up in his activity from individual drills earlier in the week, giving him a chance to return for a Week 6 game against the Patriots on Thursday. The running back initially was given an estimated recovery timeline of 4-to-8 weeks, but it's become increasingly clear he's a fast healer. Jordan Raanan of ESPN.com believes Barkley's goal all along has been a return for the matchup with New England.