NFL Player News

Mitchell (knee) is listed as questionable for Monday's game against the Ravens, Cam Inman of The San Jose Mercury News reports.

Despite not practicing Thursday or Friday, Mitchell has been given a chance to make himself available to the 49ers backfield for the first time since Week 13. Such a decision won't become known until about 90 minutes before Monday's 8:15 p.m. ET kickoff, but if Mitchell can't suit up, Jordan Mason and Jeremy McNichols will be the RB options behind top runner Christian McCaffrey.

Breida (hamstring) doesn't have an injury designation for Monday's game against the Eagles, Adam Caplan of SiriusXM NFL Radio reports.

Breida upgraded to full practice participation Friday after a pair of limited sessions. He'll likely continue to fill a reserve role behind Saquon Barkley on Sunday against the stout Eagles front.

Jacobs (quadriceps) is listed as questionable for Monday's game at Kansas City.

Jacobs was unable to practice before sitting out the Raiders' Week 15 win over the Chargers last Thursday due to a quad injury that he sustained four days earlier versus the Vikings. As Las Vegas reconvened for practice this Thursday, he managed just one limited session (Friday) during Week 16 prep while also dealing with an illness. Interim coach Antonio Pierce implied to Vic Tafur of The Athletic that because Monday's contest is a must-win situation, he expects "all the guys to play," even those that aren't healthy. Consequently, Jacobs may be trending toward a return to action, but if he's unable to do so, Zamir White likely would lead the team's backfield.

Edwards-Helaire (personal) doesn't have a designation for Monday's game against the Raiders.

Edwards-Helaire missed Friday's practice to tend to a personal matter, but he returned to drills one day later as a full participant, setting him up to be available for Week 16 action. Meanwhile, he'll welcome Isiah Pacheco back to the Chiefs backfield for the first time since Week 13, and Edwards-Helaire will be the primary complement to him, with Jerick McKinnon (groin) sidelined. On the campaign, Edwards-Helaire has averaged 3.4 yards on his 64 carries, hauled in 13 of 17 targets for 137 yards and scored two touchdowns in 13 appearances.

The Bills are elevating Fournette from the practice squad for Saturday's game against the Chargers, Ian Rapoport of NFL Network reports.

Fournette has been on Buffalo's practice squad since Oct. 30, but the veteran running back is likely to finally make his Bills debut in Saturday's Week 16 matchup. The Bills have been more reliant on the ground game in recent weeks, and while Fournette likely isn't a threat to James Cook's lead role, he could mix in as a backup option alongside Latavius Murray and possibly Ty Johnson (shoulder).

The Cowboys elevated Davis to their active roster Saturday, Michael Gehlken of The Dallas Morning News reports.

The second-year pro is now in line to appear in his third game of the season Sunday, most likely adding depth to Dallas' special teams unit. Over the course of Davis' two appearances this year, he's played a total of 31 snaps (all as a special-teamer).

McKinnon (groin) won't play Monday against the Raiders, Matt McMullen of the Chiefs' official site reports.

After not practicing Thursday and Friday, McKinnon wasn't spotted at practice Saturday and the running back is now slated to sit out Monday's contest. In his absence, look for Isiah Pacheco (who has been practicing fully this week) to lead the Chiefs' backfield versus Las Vegas, with Clyde Edwards-Helaire (personal) -- assuming his availability -- also in the mix. McKinnon will now target a potential return to action Dec. 31 against the Bengals.

McKinnon (groin) was not spotted at practice Saturday, Pete Sweeney of ArrowheadPride.com reports.

McKinnon has now failed to practice in any capacity during the week, casting significant doubt on his availability for Monday's game against the Raiders. That lines Isiah Pacheco up for a significant workload in his return from a two-game absence, with Clyde Edwards-Helaire (personal) next in line.

Moss (forearm) has been downgraded to out for Sunday's game against the Falcons.

Moss, who injured his right forearm during last Saturday's win over the Steelers, was deemed questionable for the contest after not practicing this past week, and now that he's been ruled out, he'll target a potential return to action Dec. 31 against the Raiders. While Moss will be sidelined Sunday, the Colts will welcome Jonathan Taylor (thumb) back from a three-game absence. Barring any in-game limitations or setbacks, Taylor should reclaim a leading role out of the backfield, with Trey Sermon and Tyler Goodson serving as the depth options behind him.

Mitchell (knee) didn't participate in Friday's practice, Eric Branch of the San Francisco Chronicle reports.

Mitchell has now missed both of the 49ers' first two Week 16 practices, putting him at risk of missing a third straight game Monday versus the Ravens. If Mitchell isn't able to play against Baltimore, Jordan Mason would remain in the No. 2 role behind lead back Christian McCaffrey.