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Micah McFadden LB | NYG
Giants' Micah McFadden: Won't return Sunday
McFadden (lower leg) has been ruled out for the rest of Sunday's game against the Commanders, Dan Salomone of the Giants' official site reports.
McFadden had to be carted off the field after injuring his leg while tackling Austin Ekeler in the first quarter, per Dan Duggan of The Athletic. With McFadden done for the day, Darius Muasau and Chris Board are the top candidates to work with the first-team defense at inside linebacker alongside Bobby Okereke.
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Lucas Patrick C | WAS
Bengals' Lucas Patrick: Injures calf, doubtful to return
Patrick (calf) has been deemed doubtful to return to Sunday's Week 1 matchup versus Cleveland.
Patrick was hurt early in the second quarter and limped off the field. His doubtful designation suggests he's unlikely to get back on the field Sunday. Dalton Risner has entered the game at right guard.
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Elandon Roberts OLB | PIT
Raiders' Elandon Roberts: Suffers elbow injury vs. Patriots
Roberts is questionable to return to Sunday's game against New England due to a left elbow injury, Paul Gutierrez of Raiders.com reports.
Roberts suffered the injury late in the first quarter and will undergo further tests to determine the severity of the issue. Tommy Eichenberg will see an uptick in snaps at middle linebacker for as long as Roberts is sidelined.
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Kene Nwangwu RB | NYJ
Jets' Kene Nwangwu: Exits game due to hamstring injury
Nwangwu (hamstring) is questionable to return to Sunday's game against the Steelers.
Nwangwu picked up the injury in the first quarter and is being evaluated by trainers to determine the severity of the injury. Arian Smith would figure to join Xavier Gipson on kick returns if Nwangwu is unable to return.
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Khalil Mack OLB | LAC
Chargers' Khalil Mack: Logs one tackle vs. KC
Mack registered one solo tackle and a quarterback hit during the Chargers' 27-21 win over the Chiefs on Friday.
Mack's lone tackle came on the Chiefs' second offensive play in the first quarter, when he took down Xavier Worthy (shoulder) for no gain on a rushing play. Mack opted to delay his retirement from the NFL for at least one season after re-signing with the Chargers in March, and the veteran edge rusher will play a key role in the Bolts' defense, especially following the departure of Joey Bosa to the Bills.
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James Daniels G | MIA
Dolphins' James Daniels: Exits with pec issue Sunday
Daniels is questionable to return to Sunday's Week 1 game against Indianapolis due to a pectoral injury.
Daniels departed in the first quarter and was subsequently deemed questionable to return. Kion Smith has entered the game at right guard in Daniels' stead.
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Tershawn Wharton DE | CAR
Panthers' Tershawn Wharton: Exits Sunday's game
Wharton exited Sunday's game against the Jaguars and is being evaluated for a concussion, Darin Gantt of the Panthers' official site reports.
Wharton may have taken a hit to the head during the Panthers' first defensive series of the first quarter. Jaden Crumedy would be slated to see an increased number of rotational snaps at defensive end behind A'Shawn Robinson and Derrick Brown if Wharton is not cleared to return.
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Kyler Gordon CB | CHI
Bears' Kyler Gordon: Now deemed questionable for Monday
Gordon (hamstring) was added to the Bears' injury report Sunday and is questionable for Monday's matchup against Minnesota.
Gordon dealt with a hamstring issue through much of August but wasn't initially on Chicago's injury report this week. That changed Sunday, however, as Gordon was added to the report and deemed questionable for the regular-season opener. If he's not able to suit up Monday, Nick McCloud could be asked to step into more defensive snaps than previously anticipated.
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Jayden Reed WR | GB
Packers' Jayden Reed: Slated to play Week 1
Reed (foot) remains listed as questionable but is in line to suit up Sunday against the Lions, Ian Rapoport of NFL Network reports.
Among Packers skill-position players, Reed's status for Week 1 was the biggest lingering concern for the team, but the wide receiver will play through the Jones fracture in his left foot that has bothered him for roughly one month. Confirmation of his availability for Sunday's game will come in about 90 minutes before the contest's 4:25 p.m. ET kickoff, when Green Bay will release its inactive list.
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Cam Grandy TE | CIN
Bengals' Cam Grandy: Won't play Week 1
Grandy (coach's decision) is inactive for Sunday's game against the Browns.
Grandy will be a healthy scratch for Week 1 while the Bengals go with Noah Fant, Drew Sample and Tanner Hudson as the backup tight ends behind Mike Gesicki. Grandy's next opportunity to see regular-season action is Week 2 against the Jaguars on Sunday, Sept. 14.