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Dak Prescott QB | DAL
Cowboys' Dak Prescott: Not suited up Saturday
Prescott isn't slated to play in Saturday's preseason matchup versus Seattle, Nick Harris of the Fort Worth Star-Telegram reports.
This doesn't come as a surprise, as coach Brian Schottenheimer said in early August that the team's starters won't play during the preseason. Of course, Prescott has ample NFL experience and probably doesn't need preseason games to get in tune. He'll have plenty of opportunities to shake off any offseason rust and build chemistry with his pass catchers during training-camp practices.
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Stetson Bennett QB | LAR
Rams' Stetson Bennett: Leads scoring drive in preseason win
Bennett completed four of six pass attempts for 38 yards during the Rams' 20-12 win over the Chiefs in Saturday's preseason game.
With Matthew Stafford sidelined, Bennett was named the starter for the Rams' preseason opener. He led a 13-play, 73-yard drive on the Rams' second offensive possession that ended with a 25-yard field goal from Harrison Mavis. Ty Simpson took over under center the rest of the way and put together a strong stat line, completing 21 of 25 passes for 190 yards and two scores. Bennett is listed as the Rams' QB2 on the team's unofficial depth chart, but that could change if he's outplayed by Simpson over the last two preseason games. The Rams' next exhibition contest takes place Saturday, Aug. 22, against the Saints.
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Ruben Hyppolite II LB | CHI
Bears' Ruben Hyppolite: Injures shoulder in preseason opener
Hyppolite is dealing with a shoulder injury that he suffered in Saturday's preseason win against the Browns, Courtney Cronin of ESPN.com reports.
Hyppolite led Chicago with seven tackles (four solo) in the victory and added a defensed pass, but he injured his shoulder in the second half and was unable to return. It's not clear at this point how serious the injury is, but it takes on some added significance since Hyppolite missed two games late last season due to a shoulder issue. The Maryland product is slated to serve as a rotational outside linebacker for the Bears if healthy this year.
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Bryce Young QB | CAR
Panthers' Bryce Young: Little production in preseason loss
Young completed three of five passes for 18 yards in Saturday's 29-14 preseason loss to the Bills.
The fourth-year QB got the start and played into the second quarter after sitting out the Panthers' preseason opener last week in the Hall of Fame Game, but the offense couldn't get much going as all three of Young's possessions ended in punts. The 2023 first overall pick has yet to prove he can be a franchise quarterback in the NFL, or even a reliable fantasy option, but Young did take a small step forward in 2025 by setting career highs in completion rate (63.6 percent), passing yards (3,011) and passing TDs (23) over 16 regular-season games.
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Nephi Sewell LB | CHI
Bears' Nephi Sewell: Suffers concussion Saturday
Sewell was concussed during Saturday's preseason win against Cleveland, Courtney Cronin of ESPN.com reports.
Sewell was hurt during a kickoff and spent a few minutes on the ground before exiting under his own power. He finished the game with three tackles (one solo). Sewell will need to clear the league's concussion protocol before returning to full-contact practice or playing in a game. He's trying to earn a role with Chicago as a depth linebacker and special-teamer.
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Christian McCaffrey RB | SF
49ers' Christian McCaffrey: Misses another practice Saturday
McCaffrey (undisclosed) remained sidelined during practice Saturday, Nick Wagoner of ESPN.com reports.
The 49ers haven't yet offered much detail on McCaffrey's status aside from saying that he's dealing with "tightness." The star running back didn't play in the team's preseason opener versus Tennessee on Thursday, though San Francisco held out its other key starters as well. Offensive coordinator Klay Kubiak said early in the week that the team is "just managing" McCaffrey through some soreness, and at this point there's no indication that he's at risk of not being ready for Week 1 of the regular season. Still, fantasy managers -- especially those who have upcoming drafts -- may be wise to keep an eye on the situation to monitor when McCaffrey is ready to return to the practice field.
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Kyler Gordon CB | CHI
Bears' Kyler Gordon: Timeline to return 'unkown'
Bears coach Ben Johnson said Saturday that Gordon's timeline to return to practice from his calf injury is "unknown," Courtney Cronin of ESPN.com reports.
Gordon is still dealing with the calf issue that he suffered in May. The 26-year-old was placed on the active/PUP list July 25 and hasn't been able to practice. Gordon will be a key part of the Bears secondary if healthy this season, but the ongoing injury issues are concerning after he played in only three regular-season contests last year due to soft-tissue injuries (though he did return for Chicago's two playoff games). Should Gordon not be ready for Week 1 of the regular season, Josh Blackwell could be asked to step into a starting role.
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Makai Lemon WR | PHI
Eagles' Makai Lemon: Not in line to play Saturday
Lemon isn't suited up for Saturday's preseason game in Baltimore, Brooks Kubena of The Athletic reports.
In advance of this contest, the rookie first-round pick has missed all practices since Aug. 4 due to a minor hamstring injury. Fellow WRs DeVonta Smith (hamstring) and Johnny Wilson also aren't dressed Saturday, meaning Dontayvion Wicks, Hollywood Brown, Elijah Moore and Darius Cooper are the top healthy options at the position. Lemon's next chance for his first action as a pro will arrive next Saturday at New England.
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Saquon Barkley RB | PHI
Eagles' Saquon Barkley: Not suited up Saturday
Barkley isn't in uniform for Saturday's preseason game at Baltimore, Brooks Kubena of The Athletic reports.
WRs DeVonta Smith (hamstring), Makai Lemon (hamstring) and Johnny Wilson also aren't dressed for the preseason opener, but it appears that most of the rest of the Eagles' skill-position talents may be available Saturday. When it comes to the backfield, Tank Bigsby, Will Shipley, Carson Steele and Ja'Quinden Jackson currently are the healthy options. Barkley is coming off a subpar (for him) 2025 campaign in which he churned out 1,413 yards from scrimmage and nine total touchdowns on 317 touches in 16 regular-season games.
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Jaylen Harrell DE | TEN
Titans' Jaylen Harrell: Done for season due to torn ACL
Harrell has been diagnosed with a torn ACL, Jim Wyatt of the Titans' official site reports.
Harrell's injury occurred during Thursday's preseason win over San Francisco. Per Turron Davenport of ESPN.com, the third-year linebacker will be sidelined for the entire 2026 season. It's a tough blow for Harrell and Tennessee's defense after the Michigan product showed intriguing growth with 3.5 sacks over his final four games during his 2025 sophomore campaign. He'll now look to rehab in the hope of being ready for training camp ahead of the 2027 season.